Exploring the effects of using marijuana and tobacco together

Understanding the clinical pharmacology of marijuana-tobacco co-administration

NIH-funded research University of California, San Francisco · NIH-11036347

This study is looking at how using marijuana and tobacco together affects your health, especially your heart, to help people understand the risks of mixing these substances.

Quick facts

Grant typeR01 grant
Study typeNIH-funded research
Funding institutionUniversity of California, San Francisco NIH-funded
Lab location1 site (San Francisco, United States)
Project IDNIH-11036347 on NIH RePORTER

What this research studies

This research investigates how the combined use of marijuana and tobacco affects health outcomes. It aims to understand the pharmacokinetics and pharmacodynamics of co-administration by delivering controlled doses of THC from marijuana and nicotine from tobacco using a vaporizer. By studying the interactions between these substances, the research seeks to uncover the health risks associated with their combined use, which is prevalent among users. The findings could provide valuable insights into the effects of co-use on cardiovascular health and other areas.

Who could benefit from this research

Good fit: Ideal candidates for this research are individuals who regularly use both marijuana and tobacco.

Not a fit: Patients who do not use either marijuana or tobacco may not receive any benefit from this research.

Why it matters

Potential benefit: If successful, this research could lead to better understanding and management of health risks associated with marijuana-tobacco co-use.

How similar studies have performed: While there is limited research on the combined effects of marijuana and tobacco, this study aims to fill a significant gap in understanding their co-use, making it a novel approach.

Where this research is happening

San Francisco, United States

Researchers

About this research

  1. This is an active NIH-funded research project — typically early-stage science, not a clinical trial accepting patient enrollment.
  2. Some NIH-funded labs run parallel clinical studies or seek volunteers for related work. To check, contact the principal investigator or institution listed above.
  3. For full project details, budget, and progress reports, visit the official NIH RePORTER page below.
Conditions cannabis use disorder
Last reviewed 2026-06-13 by the Find a Trial editorial team. Information on this page is for educational purposes and is not medical advice. Always consult qualified healthcare professionals about clinical trial participation.