Exploring the effects of using marijuana and tobacco together
Official title: Understanding the clinical pharmacology of marijuana-tobacco co-administration
Funded at University of California, San Francisco · NIH-11036347 · Data updated 2026-11-12
This study is looking at how using marijuana and tobacco together affects your health, especially your heart, to help people understand the risks of mixing these substances.
Quick facts
| Grant type | R01 grant |
|---|---|
| Study type | NIH-funded research |
| Funding institution | University of California, San Francisco NIH-funded |
| Lab location | 1 site (San Francisco, United States) |
| Project start | May 15, 2023 |
| Project end | February 29, 2028 |
| Funding year | 2025 |
| Award (this year) | $726,440 |
| NIH project number | 5R01DA056451-03 |
| Project ID | NIH-11036347 on NIH RePORTER |
Who could benefit from this research
✓Could help
Ideal candidates for this research are individuals who regularly use both marijuana and tobacco.
✕Less likely to help
Patients who do not use either marijuana or tobacco may not receive any benefit from this research.
What this research studies
This research investigates how the combined use of marijuana and tobacco affects health outcomes. It aims to understand the pharmacokinetics and pharmacodynamics of co-administration by delivering controlled doses of THC from marijuana and nicotine from tobacco using a vaporizer. By studying the interactions between these substances, the research seeks to uncover the health risks associated with their combined use, which is prevalent among users. The findings could provide valuable insights into the effects of co-use on cardiovascular health and other areas.
Why it matters
Potential benefit: If successful, this research could lead to better understanding and management of health risks associated with marijuana-tobacco co-use.
How similar studies have gone: While there is limited research on the combined effects of marijuana and tobacco, this study aims to fill a significant gap in understanding their co-use, making it a novel approach.
Where this research is happening
-
University of California, San Francisco
San Francisco, United States Active
Researchers
- Principal investigator: St.helen, Gideon — University of California, San Francisco
- Study coordinator: St.helen, Gideon
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About this research
- This is an active NIH-funded research project — typically early-stage science, not a clinical trial accepting patient enrollment.
- Some NIH-funded labs run parallel clinical studies or seek volunteers for related work. To check, contact the principal investigator or institution listed above.
- For full project details, budget, and progress reports, visit the official NIH RePORTER page.