Exploring the connection between viruses and cancer in people living with HIV
Official title: Partnership to Assess Viral and Immune Landscape Intersections with ONcology for People Living with HIV (PAVILION)
Funded at H. Lee Moffitt Cancer Ctr & Res Inst · NIH-10898554 · Data updated 2026-11-12
This study is looking at how certain viral infections, like HIV, HPV, and EBV, affect the immune system and may lead to different types of cancer in people living with HIV, especially in sub-Saharan Africa, to help improve cancer care for these individuals.
Quick facts
| Grant type | NIH-funded research |
|---|---|
| Study type | NIH-funded research |
| Funding institution | H. Lee Moffitt Cancer Ctr & Res Inst NIH-funded |
| Lab location | 1 site (Tampa, United States) |
| Project start | August 3, 2023 |
| Project end | July 31, 2028 |
| Funding year | 2024 |
| Award (this year) | $1,108,715 |
| NIH project number | 5U54CA277834-02 |
| Project ID | NIH-10898554 on NIH RePORTER |
Who could benefit from this research
✓Could help
Ideal candidates for this research are individuals living with HIV, particularly those in sub-Saharan Africa, who may be at risk for virus-associated cancers.
✕Less likely to help
Patients who are not living with HIV or those who do not have a history of virus-associated cancers may not benefit from this research.
What this research studies
This research investigates how viral infections, particularly HIV, HPV, and EBV, interact with the immune system to influence the development of various cancers in individuals living with HIV. The project aims to understand the unique cancer risks faced by these patients, especially in sub-Saharan Africa, where the burden of HIV and related cancers is significant. By collaborating with experienced research sites and experts, the study will focus on understudied cancers associated with these viruses, aiming to improve cancer outcomes for this vulnerable population.
Why it matters
Potential benefit: If successful, this research could lead to better prevention and treatment strategies for cancer in people living with HIV.
How similar studies have gone: Previous research has shown promising results in understanding the links between viral infections and cancer, but this specific focus on HIV-related malignancies is relatively novel.
Where this research is happening
-
H. Lee Moffitt Cancer Ctr & Res Inst
Tampa, United States Active
Researchers
- Principal investigator: Giuliano, Anna R. — H. Lee Moffitt Cancer Ctr & Res Inst
- Study coordinator: Giuliano, Anna R.
About this research
- This is an active NIH-funded research project — typically early-stage science, not a clinical trial accepting patient enrollment.
- Some NIH-funded labs run parallel clinical studies or seek volunteers for related work. To check, contact the principal investigator or institution listed above.
- For full project details, budget, and progress reports, visit the official NIH RePORTER page.