Exploring the connection between gut health and addiction

Multidisciplinary Characterization of the Gut-Brain Axis in Addiction

NIH-funded research Rutgers, the State Univ of N.j. · NIH-10908045

This study is looking at how the bacteria in our gut might affect addiction and substance use problems, and it's for anyone interested in understanding how our gut health can influence our brain and behavior, with the hope of finding better treatments for those struggling with these issues.

Quick facts

Grant typeNIH-funded research
Study typeNIH-funded research
Funding institutionRutgers, the State Univ of N.j. NIH-funded
Lab location1 site (Piscataway, United States)
Project IDNIH-10908045 on NIH RePORTER

What this research studies

This research investigates how the gut microbiota influences addiction and substance use disorders (SUDs) by examining the interactions between gut bacteria and brain function. Researchers will utilize advanced techniques like metagenomics and metabolomics to uncover the mechanisms behind these gut-brain connections. By studying both human and animal models, the project aims to identify specific pathways that may contribute to the development of SUDs, ultimately seeking to improve treatment options for affected individuals.

Who could benefit from this research

Good fit: Ideal candidates for this research are adults over 21 who are struggling with substance use disorders.

Not a fit: Patients who do not have substance use disorders or are under 21 years old may not benefit from this research.

Why it matters

Potential benefit: If successful, this research could lead to new treatment strategies for addiction by targeting gut health.

How similar studies have performed: Previous research has shown promising results in understanding the gut-brain axis, but this approach aims to provide deeper mechanistic insights that are still largely untested.

Where this research is happening

Piscataway, United States

Researchers

About this research

  1. This is an active NIH-funded research project — typically early-stage science, not a clinical trial accepting patient enrollment.
  2. Some NIH-funded labs run parallel clinical studies or seek volunteers for related work. To check, contact the principal investigator or institution listed above.
  3. For full project details, budget, and progress reports, visit the official NIH RePORTER page below.
Conditions Chronic Disease
Last reviewed 2026-06-13 by the Find a Trial editorial team. Information on this page is for educational purposes and is not medical advice. Always consult qualified healthcare professionals about clinical trial participation.