Exploring new therapies for HPV-related head and neck cancer
Integrating genomics and the protein interactome for HPV+ head and neck cancer therapy
This study is looking at how HPV causes head and neck cancer to find better and safer treatments, so patients can have new options that are less invasive and easier on their bodies.
Quick facts
| Grant type | NIH-funded research |
|---|---|
| Study type | NIH-funded research |
| Funding institution | University of California, San Francisco NIH-funded |
| Lab location | 1 site (San Francisco, United States) |
| Project ID | NIH-10875272 on NIH RePORTER |
What this research studies
This research focuses on understanding how human papillomavirus (HPV) contributes to head and neck cancer (HNC) and aims to develop more effective and less harmful treatments. By using advanced genomic techniques and studying the interactions between cancer-related proteins, the research seeks to identify new therapeutic targets that can improve patient outcomes. The project will utilize preclinical models that closely mimic HPV+ HNC to translate these findings into clinical applications. Patients may benefit from innovative treatment options that reduce the need for invasive surgeries and harsh chemoradiation.
Who could benefit from this research
Good fit: Ideal candidates for this research are individuals diagnosed with HPV+ head and neck cancer, particularly those with recurrent or metastatic disease.
Not a fit: Patients with head and neck cancers not associated with HPV may not benefit from this research.
Why it matters
Potential benefit: If successful, this research could lead to more effective and less toxic therapies for patients with HPV+ head and neck cancer.
How similar studies have performed: Previous research has shown promise in using genomic approaches to identify therapeutic targets in various cancers, suggesting potential success for this novel approach.
Where this research is happening
San Francisco, United States
- University of California, San Francisco — San Francisco, United States (Active)
Researchers
- Principal investigator: Grandis, Jennifer Rubin — University of California, San Francisco
- Study coordinator: Grandis, Jennifer Rubin
About this research
- This is an active NIH-funded research project — typically early-stage science, not a clinical trial accepting patient enrollment.
- Some NIH-funded labs run parallel clinical studies or seek volunteers for related work. To check, contact the principal investigator or institution listed above.
- For full project details, budget, and progress reports, visit the official NIH RePORTER page below.