Exploring how sugar molecules on proteins affect skin cancer
Official title: Functional Landscape of Glycosylation in Skin Cancer
Funded at Rockefeller University · NIH-10772110 · Data updated 2026-11-12
This study is looking at how sugar molecules attached to proteins might affect the growth of squamous cell carcinoma, a common skin cancer, and aims to find new treatment options that could help patients like you.
Quick facts
| Grant type | Career grant |
|---|---|
| Study type | NIH-funded research |
| Funding institution | Rockefeller University NIH-funded |
| Lab location | 1 site (New York, United States) |
| Project start | February 1, 2023 |
| Project end | January 31, 2026 |
| Funding year | 2024 |
| Award (this year) | $178,427 |
| NIH project number | 5K99CA277591-02 |
| Project ID | NIH-10772110 on NIH RePORTER |
Who could benefit from this research
✓Could help
Ideal candidates for this research are individuals diagnosed with squamous cell carcinoma or those at high risk for developing this type of skin cancer.
✕Less likely to help
Patients with other types of skin cancer or those without any malignancies may not receive direct benefits from this research.
What this research studies
This research investigates the role of glycosylation, a process where sugar molecules attach to proteins, in the development and progression of squamous cell carcinoma (SCC), a common type of skin cancer. Using a mouse model, the study aims to map changes in glycosylation patterns associated with SCC and to identify potential new therapies. The researchers will employ advanced techniques such as microscopy and genetic screening to understand how these sugar modifications influence cancer behavior and treatment responses. Patients may benefit from insights that could lead to innovative treatment strategies targeting glycosylation.
Why it matters
Potential benefit: If successful, this research could lead to new therapeutic approaches for treating skin cancer by targeting glycosylation changes.
How similar studies have gone: Other research has shown promising results in understanding glycosylation's role in cancer, suggesting that this approach could yield valuable insights.
Where this research is happening
-
Rockefeller University
New York, United States Active
Researchers
- Principal investigator: Kudelka, Matthew Robert — Rockefeller University
- Study coordinator: Kudelka, Matthew Robert
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About this research
- This is an active NIH-funded research project — typically early-stage science, not a clinical trial accepting patient enrollment.
- Some NIH-funded labs run parallel clinical studies or seek volunteers for related work. To check, contact the principal investigator or institution listed above.
- For full project details, budget, and progress reports, visit the official NIH RePORTER page.