Exploring how RNA modifications affect gene regulation
Official title: Investigating the roles of nuclear RNA modifications in gene regulation
Funded at University of California Riverside · NIH-10842996 · Data updated 2026-11-12
This study is looking at how changes to RNA can affect gene activity, which might help us understand diseases like cancer and brain disorders better, and ultimately lead to new ways to treat these conditions.
Quick facts
| Grant type | NIH-funded research |
|---|---|
| Study type | NIH-funded research |
| Funding institution | University of California Riverside NIH-funded |
| Lab location | 1 site (Riverside, United States) |
| Project start | August 1, 2024 |
| Project end | July 31, 2029 |
| Funding year | 2024 |
| Award (this year) | $393,750 |
| NIH project number | 1R35GM153225-01 |
| Project ID | NIH-10842996 on NIH RePORTER |
Who could benefit from this research
✓Could help
Ideal candidates for this research include individuals diagnosed with cancers or neurodegenerative disorders who are interested in understanding the molecular mechanisms underlying their conditions.
✕Less likely to help
Patients with conditions unrelated to RNA modifications or gene regulation may not receive direct benefits from this research.
What this research studies
This research investigates the role of RNA modifications in regulating gene expression, particularly in the context of various diseases such as cancer and neurodegenerative disorders. By utilizing advanced sequencing techniques, the study aims to uncover the different types of RNA modifications and their biological significance. Patients may benefit from insights gained about how these modifications influence disease progression and treatment responses. The research focuses on understanding the mechanisms by which RNA modifications can alter gene activity and potentially lead to new therapeutic strategies.
Why it matters
Potential benefit: If successful, this research could lead to new insights into gene regulation that may improve treatment options for patients with cancers and neurodegenerative diseases.
How similar studies have gone: Other research has shown promising results in understanding RNA modifications and their roles in gene regulation, indicating that this area of study is both relevant and potentially impactful.
Where this research is happening
-
University of California Riverside
Riverside, United States Active
Researchers
- Principal investigator: Gu, Weifeng — University of California Riverside
- Study coordinator: Gu, Weifeng
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About this research
- This is an active NIH-funded research project — typically early-stage science, not a clinical trial accepting patient enrollment.
- Some NIH-funded labs run parallel clinical studies or seek volunteers for related work. To check, contact the principal investigator or institution listed above.
- For full project details, budget, and progress reports, visit the official NIH RePORTER page.