Exploring how immune function affects social interactions in children with autism

Immune Functioning and Reward Processing in Autism

NIH-funded research Univ of North Carolina Chapel Hill · NIH-10951667

This study is looking at how kids with autism respond to social rewards and how inflammation in their bodies might affect their social skills and happiness, and it’s for children aged 0-11 years.

Quick facts

Grant typeR21 grant
Study typeNIH-funded research
Funding institutionUniv of North Carolina Chapel Hill NIH-funded
Lab location1 site (Chapel Hill, United States)
Project IDNIH-10951667 on NIH RePORTER

What this research studies

This research investigates the connections between social reward processing and inflammation in children with autism spectrum disorder (ASD). By using electroencephalography (EEG) to measure brain responses to social rewards and analyzing blood samples for inflammation markers, the study aims to understand how these factors influence social communication skills and overall quality of life. The research will involve children aged 0-11 years and seeks to uncover potential links that could inform future treatments and interventions.

Who could benefit from this research

Good fit: Ideal candidates for this research are children aged 0-11 years diagnosed with autism spectrum disorder.

Not a fit: Patients who do not have autism spectrum disorder or are outside the age range of 0-11 years may not benefit from this research.

Why it matters

Potential benefit: If successful, this research could lead to improved understanding and treatment strategies for enhancing social interactions in children with autism.

How similar studies have performed: While there is growing evidence linking inflammation to autism, this specific investigation into the relationship between immune function and social reward processing is novel and has not been extensively studied.

Where this research is happening

Chapel Hill, United States

Researchers

About this research

  1. This is an active NIH-funded research project — typically early-stage science, not a clinical trial accepting patient enrollment.
  2. Some NIH-funded labs run parallel clinical studies or seek volunteers for related work. To check, contact the principal investigator or institution listed above.
  3. For full project details, budget, and progress reports, visit the official NIH RePORTER page below.
Conditions Autistic DisorderAutoimmune Diseases
Last reviewed 2026-06-13 by the Find a Trial editorial team. Information on this page is for educational purposes and is not medical advice. Always consult qualified healthcare professionals about clinical trial participation.