Exploring how diet affects autoimmune eye diseases
Interrogating the intersection between diet and ocular autoimmunity
This study is looking at how a ketogenic diet might help people with autoimmune eye conditions, like Multiple Sclerosis and Neuromyelitis Optica, by seeing if changing what you eat can help reduce inflammation and improve treatment outcomes.
Quick facts
| Grant type | R01 grant |
|---|---|
| Study type | NIH-funded research |
| Funding institution | Oklahoma Medical Research Foundation NIH-funded |
| Lab location | 1 site (Oklahoma City, United States) |
| Project ID | NIH-11072065 on NIH RePORTER |
What this research studies
This research investigates the relationship between diet and autoimmune conditions affecting the eyes, particularly focusing on how a ketogenic diet may help manage these diseases. The study aims to understand the immune-modulating effects of this diet and its potential to enhance existing treatments for conditions like Multiple Sclerosis and Neuromyelitis Optica. By using a mouse model that mimics human autoimmune responses, researchers will explore how dietary changes can promote healing and reduce inflammation. Patients may benefit from insights into dietary interventions that could improve their condition.
Who could benefit from this research
Good fit: Ideal candidates for this research are individuals diagnosed with autoimmune diseases affecting vision, such as Multiple Sclerosis or Neuromyelitis Optica.
Not a fit: Patients with autoimmune conditions unrelated to ocular health may not receive direct benefits from this research.
Why it matters
Potential benefit: If successful, this research could lead to dietary recommendations that significantly improve the management of autoimmune eye diseases.
How similar studies have performed: Previous research has shown promising results in using dietary interventions to manage autoimmune conditions, suggesting potential for success in this approach.
Where this research is happening
Oklahoma City, United States
- Oklahoma Medical Research Foundation — Oklahoma City, United States (Active)
Researchers
- Principal investigator: Plafker, Scott M — Oklahoma Medical Research Foundation
- Study coordinator: Plafker, Scott M
About this research
- This is an active NIH-funded research project — typically early-stage science, not a clinical trial accepting patient enrollment.
- Some NIH-funded labs run parallel clinical studies or seek volunteers for related work. To check, contact the principal investigator or institution listed above.
- For full project details, budget, and progress reports, visit the official NIH RePORTER page below.