Exploring how body clocks affect infertility caused by Chlamydia
Determining the role of circadian rhythms in Chlamydia associated tubal infertility
This study is looking at how our body clocks might affect fertility issues caused by Chlamydia infections, using mice to see if the timing of the infection makes a difference in how severe the problem is, which could help us understand more about how to support those facing infertility.
Quick facts
| Grant type | NIH-funded research |
|---|---|
| Study type | NIH-funded research |
| Funding institution | Morehouse School of Medicine NIH-funded |
| Lab location | 1 site (Atlanta, United States) |
| Project ID | NIH-11074601 on NIH RePORTER |
What this research studies
This research investigates the connection between circadian rhythms, or body clocks, and tubal factor infertility caused by Chlamydia infections. The study aims to understand how the timing of infection influences the severity of the disease and its impact on fertility. By using genetically modified mice, researchers will examine the role of specific genes related to circadian rhythms in the progression of Chlamydia-related infertility. The findings could provide insights into how disruptions in natural body rhythms may exacerbate the effects of this infection.
Who could benefit from this research
Good fit: Ideal candidates for this research are women experiencing infertility issues potentially linked to Chlamydia infections.
Not a fit: Patients who do not have a history of Chlamydia infections or those whose infertility is caused by other factors may not benefit from this research.
Why it matters
Potential benefit: If successful, this research could lead to new strategies for preventing or treating infertility related to Chlamydia infections.
How similar studies have performed: While the specific focus on circadian rhythms in Chlamydia-related infertility is novel, previous research has shown that circadian rhythms can influence various biological processes and disease outcomes.
Where this research is happening
Atlanta, United States
- Morehouse School of Medicine — Atlanta, United States (Active)
Researchers
- Principal investigator: Omosun, Yusuf Oseobhunu — Morehouse School of Medicine
- Study coordinator: Omosun, Yusuf Oseobhunu
About this research
- This is an active NIH-funded research project — typically early-stage science, not a clinical trial accepting patient enrollment.
- Some NIH-funded labs run parallel clinical studies or seek volunteers for related work. To check, contact the principal investigator or institution listed above.
- For full project details, budget, and progress reports, visit the official NIH RePORTER page below.