Exploring how biological sex affects tissue repair and healing
Biomaterial technologies for interrogating sex differences in tissue repair and homeostasis
This study is looking at how being male or female affects the body's ability to heal and repair tissue, especially after menopause, and aims to find better ways to help everyone recover based on their unique needs.
Quick facts
| Grant type | NIH-funded research |
|---|---|
| Study type | NIH-funded research |
| Funding institution | University of Washington NIH-funded |
| Lab location | 1 site (Seattle, United States) |
| Project ID | NIH-10897853 on NIH RePORTER |
What this research studies
This research investigates how biological sex influences the ability to repair and regenerate tissue, particularly focusing on the effects of sex hormones on tissue health after menopause. It aims to understand the interplay between tissue structure, mechanical function, and estrogen signaling, which can impact healing processes. By developing biomaterial tools, the research seeks to uncover the mechanisms behind these sex differences, ultimately leading to improved strategies for tissue repair and regeneration tailored to individual needs.
Who could benefit from this research
Good fit: Ideal candidates for this research include postmenopausal women and individuals experiencing degenerative diseases related to tissue repair.
Not a fit: Patients who are not postmenopausal or do not have conditions related to tissue degeneration may not benefit from this research.
Why it matters
Potential benefit: If successful, this research could lead to more effective treatments for degenerative diseases that disproportionately affect women, enhancing their healing and recovery processes.
How similar studies have performed: Other research has shown promising results in understanding sex differences in tissue repair, but this specific approach using biomaterial technologies is relatively novel.
Where this research is happening
Seattle, United States
- University of Washington — Seattle, United States (Active)
Researchers
- Principal investigator: Robinson, Jennifer Lindsey — University of Washington
- Study coordinator: Robinson, Jennifer Lindsey
About this research
- This is an active NIH-funded research project — typically early-stage science, not a clinical trial accepting patient enrollment.
- Some NIH-funded labs run parallel clinical studies or seek volunteers for related work. To check, contact the principal investigator or institution listed above.
- For full project details, budget, and progress reports, visit the official NIH RePORTER page below.