Exploring how biological clocks in cells maintain stability
Understanding the robustness of cell cycles
This study is looking at how natural rhythms in our bodies, like those that control cell division and heartbeats, work and stay steady even when things around them change, which could help people understand and treat conditions like cancer or insomnia.
Quick facts
| Grant type | R01 grant |
|---|---|
| Study type | NIH-funded research |
| Funding institution | University of Michigan at Ann Arbor NIH-funded |
| Lab location | 1 site (Ann Arbor, United States) |
| Project ID | NIH-11038023 on NIH RePORTER |
What this research studies
This research investigates the mechanisms behind biological oscillators, which are crucial for processes like cell division and heartbeats. By using a combination of computational analysis and experimental methods, the study aims to understand how these oscillators can remain stable despite changes in their environment. Patients may benefit from insights gained about how disruptions in these oscillators can lead to diseases such as cancer or insomnia. The research employs innovative techniques, including a droplet-based microfluidic system to simulate cell cycles.
Who could benefit from this research
Good fit: Ideal candidates for this research are individuals affected by conditions related to biological oscillators, such as cancer or sleep disorders.
Not a fit: Patients with conditions unrelated to biological oscillators may not receive any benefit from this research.
Why it matters
Potential benefit: If successful, this research could lead to new strategies for treating diseases linked to dysfunctional biological oscillators.
How similar studies have performed: Other research has shown promising results in understanding biological oscillators, suggesting that this approach could yield valuable insights.
Where this research is happening
Ann Arbor, United States
- University of Michigan at Ann Arbor — Ann Arbor, United States (Active)
Researchers
- Principal investigator: Yang, Qiong — University of Michigan at Ann Arbor
- Study coordinator: Yang, Qiong
About this research
- This is an active NIH-funded research project — typically early-stage science, not a clinical trial accepting patient enrollment.
- Some NIH-funded labs run parallel clinical studies or seek volunteers for related work. To check, contact the principal investigator or institution listed above.
- For full project details, budget, and progress reports, visit the official NIH RePORTER page below.