Exploring how bacteria affect brain development and function in a squid.
Determining the Role of Bacterial Products on Neuronal Localization and Function in a Symbiotic Organ
This study looks at how bacteria can affect the nervous system by using the Hawaiian bobtail squid and its glowing bacteria buddy, helping us learn more about how gut bacteria might impact brain health.
Quick facts
| Grant type | R21 grant |
|---|---|
| Study type | NIH-funded research |
| Funding institution | Michigan State University NIH-funded |
| Lab location | 1 site (East Lansing, United States) |
| Project ID | NIH-10832627 on NIH RePORTER |
What this research studies
This research investigates the relationship between bacteria and the nervous system using the Hawaiian bobtail squid and its luminescent bacterial partner. By studying this unique symbiotic relationship, the researchers aim to understand how bacterial products influence neuronal development and function. The approach involves manipulating the squid model to observe changes in brain activity and development in response to different bacterial influences. This could provide insights into the broader implications of gut microbiota on brain health.
Who could benefit from this research
Good fit: Ideal candidates for this research are individuals interested in the effects of gut bacteria on neurological health and development.
Not a fit: Patients with conditions unrelated to gut microbiota or neurological function may not benefit from this research.
Why it matters
Potential benefit: If successful, this research could lead to new strategies for improving brain health and function through microbiome modulation.
How similar studies have performed: Previous research has shown promising results in understanding the impact of gut microbiota on brain function, making this approach both relevant and potentially groundbreaking.
Where this research is happening
East Lansing, United States
- Michigan State University — East Lansing, United States (Active)
Researchers
- Principal investigator: Heath-Heckman, Elizabeth a. — Michigan State University
- Study coordinator: Heath-Heckman, Elizabeth a.
About this research
- This is an active NIH-funded research project — typically early-stage science, not a clinical trial accepting patient enrollment.
- Some NIH-funded labs run parallel clinical studies or seek volunteers for related work. To check, contact the principal investigator or institution listed above.
- For full project details, budget, and progress reports, visit the official NIH RePORTER page below.