Exploring genetic factors in severe mental illness among Latin American and African populations

4/4 Powering Genetic Discovery for Severe Mental Illness in Latin American and African Ancestries

NIH-funded research University of California Los Angeles · NIH-10918279

This study is looking at the genes that might be linked to schizophrenia and bipolar disorder, especially in people from Latin American and African backgrounds, to help us better understand these conditions and improve care for everyone.

Quick facts

Grant typeU01 cooperative agreement
Study typeNIH-funded research
Funding institutionUniversity of California Los Angeles NIH-funded
Lab location1 site (Los Angeles, United States)
Project IDNIH-10918279 on NIH RePORTER

What this research studies

This research aims to uncover genetic factors associated with schizophrenia and bipolar disorder, focusing on individuals of Latin American and African ancestries. By expanding the diversity of genetic studies, the project will analyze genetic data from 120,000 samples, including those already sequenced, to identify new genes linked to these mental health conditions. The collaboration involves leading experts in psychiatric genetics and aims to reduce health disparities by enhancing our understanding of these disorders in underrepresented populations.

Who could benefit from this research

Good fit: Ideal candidates for this research include individuals of Latin American and African descent who have been diagnosed with schizophrenia or bipolar disorder.

Not a fit: Patients who do not belong to Latin American or African ancestries may not receive direct benefits from this research.

Why it matters

Potential benefit: If successful, this research could lead to improved diagnosis and treatment options for severe mental illnesses in diverse populations.

How similar studies have performed: Previous research has shown success in genetic discovery for mental illnesses in other populations, but this approach is novel in its focus on Latin American and African ancestries.

Where this research is happening

Los Angeles, United States

Researchers

About this research

  1. This is an active NIH-funded research project — typically early-stage science, not a clinical trial accepting patient enrollment.
  2. Some NIH-funded labs run parallel clinical studies or seek volunteers for related work. To check, contact the principal investigator or institution listed above.
  3. For full project details, budget, and progress reports, visit the official NIH RePORTER page below.
Conditions Affective DisordersBipolar Disorder
Last reviewed 2026-06-13 by the Find a Trial editorial team. Information on this page is for educational purposes and is not medical advice. Always consult qualified healthcare professionals about clinical trial participation.