Exploring brain circuits in primates using advanced light technology
High density chronic optogenetic interface for primate brains
['FUNDING_SBIR_2'] · BLACKROCK MICROSYSTEMS · NIH-10706899
This study is exploring how brain circuits work in monkeys to help us understand human brain disorders better, using a special tool that lets researchers control brain activity and see how different parts of the brain talk to each other.
Quick facts
| Phase | ['FUNDING_SBIR_2'] |
|---|---|
| Study type | Nih_funding |
| Sex | All |
| Sponsor | BLACKROCK MICROSYSTEMS (nih funded) |
| Locations | 1 site (SALT LAKE CITY, UNITED STATES) |
| Trial ID | NIH-10706899 on ClinicalTrials.gov |
What this research studies
This research focuses on understanding how neural circuits function in the brains of non-human primates, which are the closest models to humans. By utilizing a cutting-edge optogenetic tool called the Utah Optrode Array, the researchers aim to manipulate large volumes of brain tissue to observe how different areas communicate and process information. This approach allows for precise control of brain activity, which could lead to insights into various brain disorders. The ultimate goal is to develop this technology into a commercial device that can be used for further studies and potential therapeutic applications.
Who could benefit from this research
Good fit: Ideal candidates for this research are individuals with neurological conditions that affect brain function, particularly those related to epilepsy or other seizure disorders.
Not a fit: Patients with conditions unrelated to brain function or those who do not have access to the research facility may not benefit from this research.
Why it matters
Potential benefit: If successful, this research could lead to new treatments for brain disorders by enhancing our understanding of brain function and connectivity.
How similar studies have performed: Previous research using optogenetic techniques in animal models has shown promising results, indicating that this approach could be effective in understanding and treating brain disorders.
Where this research is happening
SALT LAKE CITY, UNITED STATES
- BLACKROCK MICROSYSTEMS — SALT LAKE CITY, UNITED STATES (ACTIVE)
Researchers
- Principal investigator: NEGI, SANDEEP — BLACKROCK MICROSYSTEMS
- Study coordinator: NEGI, SANDEEP
About this research
- This is an active NIH-funded research project — typically early-stage science, not a clinical trial accepting patient enrollment.
- Some NIH-funded labs run parallel clinical studies or seek volunteers for related work. To check, contact the principal investigator or institution listed above.
- For full project details, budget, and progress reports, visit the official NIH RePORTER page below.
Conditions: Brain Diseases, Brain Disorders, Encephalon Diseases, Intracranial CNS Disorders, Intracranial Central Nervous System Disorders