Exploring brain circuits in primates using advanced light technology
Official title: High density chronic optogenetic interface for primate brains
Funded at Blackrock Microsystems · NIH-10706899 · Data updated 2026-11-12
This study is exploring how brain circuits work in monkeys to help us understand human brain disorders better, using a special tool that lets researchers control brain activity and see how different parts of the brain talk to each other.
Quick facts
| Grant type | Sbir 2 grant |
|---|---|
| Study type | NIH-funded research |
| Funding institution | Blackrock Microsystems NIH-funded |
| Lab location | 1 site (Salt Lake City, United States) |
| Project start | August 1, 2023 |
| Project end | July 31, 2025 |
| Funding year | 2023 |
| Award (this year) | $496,413 |
| NIH project number | 1R44MH135529-01A1 |
| Project ID | NIH-10706899 on NIH RePORTER |
Who could benefit from this research
✓Could help
Ideal candidates for this research are individuals with neurological conditions that affect brain function, particularly those related to epilepsy or other seizure disorders.
✕Less likely to help
Patients with conditions unrelated to brain function or those who do not have access to the research facility may not benefit from this research.
What this research studies
This research focuses on understanding how neural circuits function in the brains of non-human primates, which are the closest models to humans. By utilizing a cutting-edge optogenetic tool called the Utah Optrode Array, the researchers aim to manipulate large volumes of brain tissue to observe how different areas communicate and process information. This approach allows for precise control of brain activity, which could lead to insights into various brain disorders. The ultimate goal is to develop this technology into a commercial device that can be used for further studies and potential therapeutic applications.
Why it matters
Potential benefit: If successful, this research could lead to new treatments for brain disorders by enhancing our understanding of brain function and connectivity.
How similar studies have gone: Previous research using optogenetic techniques in animal models has shown promising results, indicating that this approach could be effective in understanding and treating brain disorders.
Where this research is happening
-
Blackrock Microsystems
Salt Lake City, United States Active
Researchers
- Principal investigator: Negi, Sandeep — Blackrock Microsystems
- Study coordinator: Negi, Sandeep
Related research
Other NIH-funded projects on the same topics.
-
Improving communication for ALS patients using brain-controlled interfaces
This study is looking at how special brain-computer interfaces can help people with ALS communicate better, so they can share their thoughts and feelings more easily and improve their quality of life.
About this research
- This is an active NIH-funded research project — typically early-stage science, not a clinical trial accepting patient enrollment.
- Some NIH-funded labs run parallel clinical studies or seek volunteers for related work. To check, contact the principal investigator or institution listed above.
- For full project details, budget, and progress reports, visit the official NIH RePORTER page.