Exploring bacterial outer membrane vesicles for diagnostics and therapies
Official title: Bacteria and pathogen characterizations using outer membrane vesicles
Funded at Numentus Technologies INC. · NIH-10602343 · Data updated 2026-11-12
This study is exploring how tiny bubbles released by bacteria could help us find and treat infections better by looking closely at what’s inside them, making it easier to identify specific bacterial infections.
Quick facts
| Grant type | Sbir 1 grant |
|---|---|
| Study type | NIH-funded research |
| Funding institution | Numentus Technologies INC. NIH-funded |
| Lab location | 1 site (Menlo Park, United States) |
| Project start | July 3, 2023 |
| Project end | June 30, 2026 |
| Funding year | 2023 |
| Award (this year) | $298,794 |
| NIH project number | 1R43AI174576-01 |
| Project ID | NIH-10602343 on NIH RePORTER |
Who could benefit from this research
✓Could help
Ideal candidates for this research are individuals with bacterial infections or those at risk of developing such infections.
✕Less likely to help
Patients with viral infections or non-infectious diseases may not receive any benefit from this research.
What this research studies
This research investigates the potential of outer membrane vesicles (OMVs) shed by bacteria as a source for new diagnostic and therapeutic tools. By developing a novel imaging platform, the project aims to analyze the unique protein and nucleic acid content of these vesicles at a single particle level. This approach could help identify specific bacterial infections and improve treatment strategies by providing detailed insights into the presence and characteristics of pathogenic bacteria in various biological samples.
Why it matters
Potential benefit: If successful, this research could lead to more accurate diagnostics and targeted therapies for bacterial infections.
How similar studies have gone: Other research has shown promise in utilizing extracellular vesicles for diagnostics, indicating that this approach could be a significant advancement in the field.
Where this research is happening
-
Numentus Technologies INC.
Menlo Park, United States Active
Researchers
- Principal investigator: Faris, Gregory W — Numentus Technologies INC.
- Study coordinator: Faris, Gregory W
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About this research
- This is an active NIH-funded research project — typically early-stage science, not a clinical trial accepting patient enrollment.
- Some NIH-funded labs run parallel clinical studies or seek volunteers for related work. To check, contact the principal investigator or institution listed above.
- For full project details, budget, and progress reports, visit the official NIH RePORTER page.