Exploring a new factor that affects muscle performance and metabolism
Identifying a novel player in skeletal muscle performance and metabolism
This study is looking at a protein called FSP27 to see how it affects muscle strength and insulin use, which could help us find better ways to improve muscle function and manage conditions like diabetes.
Quick facts
| Grant type | R01 grant |
|---|---|
| Study type | NIH-funded research |
| Funding institution | Ohio University Athens NIH-funded |
| Lab location | 1 site (Athens, United States) |
| Project ID | NIH-11057608 on NIH RePORTER |
What this research studies
This research investigates the role of a specific protein, Fat Specific Protein 27 (FSP27), in regulating muscle function and insulin signaling. By studying both human muscle samples and a specially designed mouse model, the researchers aim to uncover how FSP27 influences muscle strength, endurance, and metabolic health. The approach includes analyzing muscle performance metrics and understanding the molecular pathways involved in fat handling within muscle tissue. This could lead to insights into how to improve muscle function and manage metabolic diseases.
Who could benefit from this research
Good fit: Ideal candidates for this research are individuals experiencing metabolic disorders, such as adult-onset diabetes, who may benefit from improved muscle function.
Not a fit: Patients with conditions unrelated to muscle performance or metabolic regulation may not receive any benefit from this research.
Why it matters
Potential benefit: If successful, this research could lead to new strategies for enhancing muscle performance and improving insulin sensitivity in patients, potentially benefiting those with metabolic diseases.
How similar studies have performed: Previous research has shown promising results in understanding the role of muscle proteins in metabolic health, suggesting that this approach could yield valuable insights.
Where this research is happening
Athens, United States
- Ohio University Athens — Athens, United States (Active)
Researchers
- Principal investigator: Puri, Vishwajeet — Ohio University Athens
- Study coordinator: Puri, Vishwajeet
About this research
- This is an active NIH-funded research project — typically early-stage science, not a clinical trial accepting patient enrollment.
- Some NIH-funded labs run parallel clinical studies or seek volunteers for related work. To check, contact the principal investigator or institution listed above.
- For full project details, budget, and progress reports, visit the official NIH RePORTER page below.