Evaluating new medications to help treat opioid use disorders
A Clinical Laboratory with Integrated Neuroscience (CLIN) for Early Evaluation of Medications for Substance Use Disorders
This study is looking for better ways to help people with opioid use disorders by testing new medications that could also help reduce the use of other drugs like cocaine, making it easier for them to stick to their treatment.
Quick facts
| Grant type | NIH-funded research |
|---|---|
| Study type | NIH-funded research |
| Funding institution | University of Pennsylvania NIH-funded |
| Lab location | 1 site (Philadelphia, United States) |
| Project ID | NIH-10783049 on NIH RePORTER |
What this research studies
This research focuses on addressing the opioid crisis by evaluating the effectiveness of medication-assisted treatments (MAT) for individuals struggling with opioid use disorders. It aims to identify additional medications that can help reduce the use of illicit drugs, such as cocaine, which often complicates treatment adherence. By integrating neuroscience with clinical trials, the study will measure how these medications interact with the brain, potentially leading to more effective treatment options. The research is conducted in collaboration with local addiction resources to enhance the support available for patients.
Who could benefit from this research
Good fit: Ideal candidates for this research are individuals diagnosed with opioid use disorders who may also be using other illicit substances.
Not a fit: Patients who are not struggling with opioid use disorders or who do not require medication-assisted treatment may not benefit from this research.
Why it matters
Potential benefit: If successful, this research could lead to improved treatment options for patients with opioid use disorders, ultimately reducing overdose deaths and enhancing recovery outcomes.
How similar studies have performed: Previous research has shown promise in using adjunctive medications to improve outcomes in substance use disorders, indicating that this approach could be effective.
Where this research is happening
Philadelphia, United States
- University of Pennsylvania — Philadelphia, United States (Active)
Researchers
- Principal investigator: Kampman, Kyle Matthew — University of Pennsylvania
- Study coordinator: Kampman, Kyle Matthew
About this research
- This is an active NIH-funded research project — typically early-stage science, not a clinical trial accepting patient enrollment.
- Some NIH-funded labs run parallel clinical studies or seek volunteers for related work. To check, contact the principal investigator or institution listed above.
- For full project details, budget, and progress reports, visit the official NIH RePORTER page below.