Evaluating insomnia treatment to lower heart disease risk in PTSD patients

An evaluation of insomnia treatment to reduce cardiovascular risk in patients with posttraumatic stress disorder

NIH-funded research Duke University · NIH-10890044

This study is looking at how helping people with PTSD sleep better can also lower their chances of heart problems, using a special therapy called CBT-I to improve their sleep and checking their heart health along the way.

Quick facts

Grant typeR01 grant
Study typeNIH-funded research
Funding institutionDuke University NIH-funded
Lab location1 site (Durham, United States)
Project IDNIH-10890044 on NIH RePORTER

What this research studies

This research investigates how treating insomnia in patients with posttraumatic stress disorder (PTSD) can reduce their risk of cardiovascular disease. The study will utilize cognitive behavioral therapy for insomnia (CBT-I) to improve sleep quality and assess its effects on various cardiovascular health markers. Patients will undergo tests to measure blood pressure, vascular function, and sympathetic nervous system activity, which are crucial for understanding heart health. The goal is to uncover the relationship between improved sleep and reduced cardiovascular risks in this vulnerable population.

Who could benefit from this research

Good fit: Ideal candidates for this research are adults over 21 years old who have been diagnosed with PTSD and experience insomnia.

Not a fit: Patients without PTSD or those who do not experience insomnia may not benefit from this research.

Why it matters

Potential benefit: If successful, this research could lead to effective treatments that significantly lower cardiovascular risks for patients suffering from PTSD.

How similar studies have performed: Previous research has shown promising results in using cognitive behavioral therapy to improve sleep and health outcomes, suggesting potential success for this approach.

Where this research is happening

Durham, United States

Researchers

About this research

  1. This is an active NIH-funded research project — typically early-stage science, not a clinical trial accepting patient enrollment.
  2. Some NIH-funded labs run parallel clinical studies or seek volunteers for related work. To check, contact the principal investigator or institution listed above.
  3. For full project details, budget, and progress reports, visit the official NIH RePORTER page below.
Conditions Atherosclerotic Cardiovascular DiseaseCardiovascular Diseases
Last reviewed 2026-06-13 by the Find a Trial editorial team. Information on this page is for educational purposes and is not medical advice. Always consult qualified healthcare professionals about clinical trial participation.