Evaluating a new therapy for individuals with PTSD and borderline personality disorder.
Official title: A PILOT EFFECTIVENESS TRIAL OF COGNITIVE PROCESSING THERAPY AUGMENTED WITH SUICIDE RISK MANAGEMENT FOR INDIVIDUALS WITH COMORBID PTSD AND BPD
Funded at Palo Alto University · NIH-10775720 · Data updated 2026-11-12
This study is testing a new therapy that combines talking therapy for PTSD with special support for managing suicide risk, designed for people who have both PTSD and borderline personality disorder, to see if it helps them feel better in everyday life.
Quick facts
| Grant type | NIH-funded research |
|---|---|
| Study type | NIH-funded research |
| Funding institution | Palo Alto University NIH-funded |
| Lab location | 1 site (Palo Alto, United States) |
| Project start | February 1, 2022 |
| Project end | January 31, 2026 |
| Funding year | 2024 |
| Award (this year) | $168,636 |
| NIH project number | 5R34MH124968-03 |
| Project ID | NIH-10775720 on NIH RePORTER |
Who could benefit from this research
✓Could help
Ideal candidates for this research are adults aged 21 and older who have been diagnosed with both PTSD and BPD.
✕Less likely to help
Patients who do not have a diagnosis of PTSD or BPD, or those who are under 21 years old, may not benefit from this research.
What this research studies
This research investigates a new treatment approach that combines Cognitive Processing Therapy with a suicide risk management protocol for individuals suffering from both posttraumatic stress disorder (PTSD) and borderline personality disorder (BPD). The study aims to address the significant challenges faced by patients with these comorbid conditions, including heightened suicide risk and functional impairment. By utilizing a pilot effectiveness trial, the research will assess the feasibility and effectiveness of this integrated therapy in a real-world outpatient setting. Participants will receive care from community clinicians trained in this innovative approach.
Why it matters
Potential benefit: If successful, this research could provide a more effective treatment option for individuals struggling with the dual challenges of PTSD and BPD, potentially reducing suicide risk and improving overall quality of life.
How similar studies have gone: While there is limited research specifically on this combined approach, existing studies have shown promise in treating PTSD and BPD separately, suggesting potential for success in this integrated method.
Where this research is happening
-
Palo Alto University
Palo Alto, United States Active
Researchers
- Principal investigator: Kuo, Janice Rose — Palo Alto University
- Study coordinator: Kuo, Janice Rose
Related research
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About this research
- This is an active NIH-funded research project — typically early-stage science, not a clinical trial accepting patient enrollment.
- Some NIH-funded labs run parallel clinical studies or seek volunteers for related work. To check, contact the principal investigator or institution listed above.
- For full project details, budget, and progress reports, visit the official NIH RePORTER page.