Establishing and Validating Outcome Measures for Craniofacial Morphea Across the Lifespan
Funded at Ut Southwestern Medical Center · NIH-11448641 · Data updated 2026-11-12
This grant aims to create and test reliable tools to measure how craniofacial morphea affects people from childhood to adulthood.
Quick facts
| Grant type | R01 grant |
|---|---|
| Study type | NIH-funded research |
| Funding institution | Ut Southwestern Medical Center NIH-funded |
| Lab location | 1 site (Dallas, United States) |
| Project start | September 17, 2026 |
| Project end | August 31, 2030 |
| Funding year | 2026 |
| Award (this year) | $222,356 |
| NIH project number | 1R01AR088597-01 |
| Project ID | NIH-11448641 on NIH RePORTER |
Who could benefit from this research
✓Could help
Children (0-11 years) and adults (21+ years) with craniofacial morphea who can participate in imaging, clinical assessments, and surveys.
✕Less likely to help
Patients who cannot participate in imaging or lengthy assessments may have limited benefit.
What this research studies
Craniofacial morphea is a rare autoimmune condition that causes lasting facial changes and functional problems. The project will adapt and validate clinical assessments, 3D facial imaging, and patient-reported outcomes for people with this condition across all ages. By using large patient registries and a multidisciplinary team, researchers will refine tools to track symptoms, appearance, and quality of life, enabling better clinical trial readiness and treatment evaluation.
Why it matters
Potential benefit: If successful, patients could benefit from better tools to monitor disease impact and track responses to therapies.
How similar studies have gone: This work builds on existing imaging and patient-reported outcome measures and adapts them for craniofacial morphea across ages.
Where this research is happening
-
Ut Southwestern Medical Center
Dallas, United States Active
Researchers
- Principal investigator: Jacobe, Heidi T — Ut Southwestern Medical Center
- Study coordinator: Jacobe, Heidi T
About this research
- This is an active NIH-funded research project — typically early-stage science, not a clinical trial accepting patient enrollment.
- Some NIH-funded labs run parallel clinical studies or seek volunteers for related work. To check, contact the principal investigator or institution listed above.
- For full project details, budget, and progress reports, visit the official NIH RePORTER page.