NIH-funded research NIH-funded research

Epigenomics Core: newer DNA regulation services for researchers

Official title: Epigenomics Core

Funded at Oklahoma Medical Research Foundation · NIH-11349613 · Data updated 2026-11-12

A core facility upgrade at a medical research center will add advanced DNA accessibility, protein binding, and long-read sequencing services to support genomic regulation and immunity studies.

Quick facts

Grant typeNIH-funded research
Study typeNIH-funded research
Funding institutionOklahoma Medical Research Foundation
NIH-funded
Lab location1 site (Oklahoma City, United States)
Project startJune 10, 2025
Project endApril 30, 2030
Funding year2026
Award (this year)$246,431
NIH project number5P20GM156711-02
Project IDNIH-11349613 on NIH RePORTER

Who could benefit from this research

Could help

Ideal candidates are patients with immune-related conditions whose biology is studied through genomic regulation approaches or who participate via data or sample contributions in future translational projects.

Less likely to help

Patients not directly involved in immune-regulation research or unrelated conditions may not experience direct benefits from this core.

What this research studies

If you’re a patient near Oklahoma City, this project helps scientists access state-of-the-art tools to study how genes are turned on or off in immune cells. The Epigenomics Core will expand capabilities like ATAC-seq, CUT&RUN/CUT&TAG, ChIP-seq, and long-read sequencing to support diverse user projects. By improving these services, researchers can translate findings about gene regulation into better understanding of immune-related diseases and their treatment. The core focuses on enabling researchers to generate high-quality data more efficiently and sustainably at OKMRF.

Why it matters

Potential benefit: It could accelerate discoveries that improve diagnosis, treatment, and prevention of immune-related conditions.

How similar studies have gone: Other institutions have successfully expanded cores to provide chromatin accessibility and binding protein analyses, showing strong potential for impactful research advances.

Where this research is happening

  • Oklahoma Medical Research Foundation
    Oklahoma City, United States
    Active

Researchers

  • Principal investigator: Wiley, Graham — Oklahoma Medical Research Foundation
  • Study coordinator: Wiley, Graham

About this research

  1. This is an active NIH-funded research project — typically early-stage science, not a clinical trial accepting patient enrollment.
  2. Some NIH-funded labs run parallel clinical studies or seek volunteers for related work. To check, contact the principal investigator or institution listed above.
  3. For full project details, budget, and progress reports, visit the official NIH RePORTER page.
Last reviewed 2026-11-14 by the Find a Trial editorial team. Information on this page is for educational purposes and is not medical advice. Always consult qualified healthcare professionals about clinical trial participation.