Enhancing hand movement control for amputees using nerve signals

Improving hand kinematic predictions from implanted EMG in humans and monkeys

NIH-funded research University of Michigan at Ann Arbor · NIH-10979725

This study is working on a new way to help people with upper limb amputations control prosthetic hands more naturally by using signals from their nerves, making it easier for them to move their fingers and wrists just like they would with real hands.

Quick facts

Grant typeR01 grant
Study typeNIH-funded research
Funding institutionUniversity of Michigan at Ann Arbor NIH-funded
Lab location1 site (Ann Arbor, United States)
Project IDNIH-10979725 on NIH RePORTER

What this research studies

This research focuses on improving the control of prosthetic hands for individuals with upper limb amputations by utilizing electrical signals from nerves. The team has developed a method called the Regenerative Peripheral Nerve Interface (RPNI), which allows for better signal acquisition from nerve fascicles. By employing advanced deep learning techniques, the project aims to enable continuous and simultaneous control of finger and wrist movements in both humans and monkeys. This innovative approach seeks to restore more natural hand functions for amputees, enhancing their ability to perform daily activities.

Who could benefit from this research

Good fit: Ideal candidates for this research are individuals with upper limb amputations who are seeking improved control over their prosthetic devices.

Not a fit: Patients with lower limb amputations or those who do not use prosthetic devices may not benefit from this research.

Why it matters

Potential benefit: If successful, this research could significantly improve the functionality and usability of prosthetic hands for amputees, leading to greater independence in daily life.

How similar studies have performed: Previous research has shown promise in using similar deep learning techniques for brain-machine interfaces, indicating potential success for this novel approach.

Where this research is happening

Ann Arbor, United States

Researchers

About this research

  1. This is an active NIH-funded research project — typically early-stage science, not a clinical trial accepting patient enrollment.
  2. Some NIH-funded labs run parallel clinical studies or seek volunteers for related work. To check, contact the principal investigator or institution listed above.
  3. For full project details, budget, and progress reports, visit the official NIH RePORTER page below.
Last reviewed 2026-06-09 by the Find a Trial editorial team. Information on this page is for educational purposes and is not medical advice. Always consult qualified healthcare professionals about clinical trial participation.