Enhancing Breast Cancer Trial Engagement with Digital Tools and Leadership
Official title: Enhancing NCI Clinical Trial Engagement Through Digital Innovation and Leadership
Funded at Sloan-Kettering Inst Can Research · NIH-11447330 · Data updated 2026-11-12
A physician-lead grant to speed breast cancer trials by using a smart digital platform to match patients with trials and improve trial operations.
Quick facts
| Grant type | NIH-funded research |
|---|---|
| Study type | NIH-funded research |
| Funding institution | Sloan-Kettering Inst Can Research NIH-funded |
| Lab location | 1 site (New York, United States) |
| Project start | September 18, 2026 |
| Project end | August 31, 2031 |
| Funding year | 2026 |
| Award (this year) | $138,388 |
| NIH project number | 1R50CA304999-01A1 |
| Project ID | NIH-11447330 on NIH RePORTER |
Who could benefit from this research
✓Could help
Adults with breast cancer who are potential candidates for NCI-sponsored clinical trials and are seeking participation in advanced trial concepts.
✕Less likely to help
Patients seeking standard-of-care treatment with no interest or eligibility for trials, or those unable to participate in trial enrollment processes.
What this research studies
This grant supports expanding a novel, language-model–based system that helps match patients to NCI-sponsored breast cancer trials at a major cancer center. It also funds leadership and mentorship to speed trial design, accrual, and collaboration across the NCTN, with a focus on consolidative therapy, ultra-hypofractionated radiation, and pre-operative image guidance. The work includes refining digital tools for patient-trial matching, validating them within the center, and scaling them for broader adoption in NCTN networks. Patients could benefit from faster access to appropriate trials and more personalized trial options through improved availability and coordination.
Why it matters
Potential benefit: If successful, patients may experience quicker and more precise access to suitable breast cancer trials and potentially improved treatment options.
How similar studies have gone: A proof-of-concept for a language-model–based patient-trial matching platform has shown feasibility, with plans for internal validation.
Where this research is happening
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Sloan-Kettering Inst Can Research
New York, United States Active
Researchers
- Principal investigator: Braunstein, Lior Z — Sloan-Kettering Inst Can Research
- Study coordinator: Braunstein, Lior Z
About this research
- This is an active NIH-funded research project — typically early-stage science, not a clinical trial accepting patient enrollment.
- Some NIH-funded labs run parallel clinical studies or seek volunteers for related work. To check, contact the principal investigator or institution listed above.
- For full project details, budget, and progress reports, visit the official NIH RePORTER page.