Effects of subway air particles on human lung cells
Official title: Cellular effects of subway air particles in human lung cells
Funded at Villanova University · NIH-10360016 · Data updated 2026-11-12
This study looks at how the air in subway stations might affect lung cells, comparing it to air in other city areas, to help understand the health risks of breathing in subway air.
Quick facts
| Grant type | R15 grant |
|---|---|
| Study type | NIH-funded research |
| Funding institution | Villanova University NIH-funded |
| Lab location | 1 site (Villanova, United States) |
| Project start | December 1, 2021 |
| Project end | November 30, 2025 |
| Funding year | 2022 |
| Award (this year) | $346,692 |
| NIH project number | 1R15ES032588-01A1 |
| Project ID | NIH-10360016 on NIH RePORTER |
Who could benefit from this research
✓Could help
Ideal candidates for this research are individuals who frequently use subway systems and may be exposed to high levels of air pollution.
✕Less likely to help
Patients who do not use subway systems or are not exposed to urban air pollution may not benefit from this research.
What this research studies
This research investigates how air particles found in subway systems affect human lung cells. By comparing air quality from underground subway stations in Philadelphia to aboveground urban and suburban locations, the study aims to understand the cytotoxic and oxidative stress responses of lung epithelial cells to various particulate matter components. The researchers will analyze samples to determine the impact of metals and organic compounds on cellular health, providing insights into the potential risks associated with subway air pollution.
Why it matters
Potential benefit: If successful, this research could lead to improved understanding of the health risks posed by subway air pollution and inform public health policies.
How similar studies have gone: Previous research has shown that particulate matter from urban environments can significantly impact lung health, suggesting that this study builds on established findings.
Where this research is happening
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Villanova University
Villanova, United States Active
Researchers
- Principal investigator: Shakya, Kabindra Man — Villanova University
- Study coordinator: Shakya, Kabindra Man
About this research
- This is an active NIH-funded research project — typically early-stage science, not a clinical trial accepting patient enrollment.
- Some NIH-funded labs run parallel clinical studies or seek volunteers for related work. To check, contact the principal investigator or institution listed above.
- For full project details, budget, and progress reports, visit the official NIH RePORTER page.