Effects of manmade chemicals on blood vessel health
Official title: Impact of Per/Polyfluoroalkyl pollutants on vascular disease mechanisms
Funded at Boston University Medical Campus · NIH-10751239 · Data updated 2026-11-12
This study is looking at how certain chemicals found in everyday products might harm your blood vessels and lead to heart problems, and it involves both people and mice to help us understand how these chemicals affect your health.
Quick facts
| Grant type | R21 grant |
|---|---|
| Study type | NIH-funded research |
| Funding institution | Boston University Medical Campus NIH-funded |
| Lab location | 1 site (Boston, United States) |
| Project start | July 1, 2023 |
| Project end | June 30, 2025 |
| Funding year | 2023 |
| Award (this year) | $453,750 |
| NIH project number | 1R21ES034939-01A1 |
| Project ID | NIH-10751239 on NIH RePORTER |
Who could benefit from this research
✓Could help
Ideal candidates for this research include individuals exposed to PFAS through environmental or occupational sources who are at risk for cardiovascular diseases.
✕Less likely to help
Patients who are not exposed to PFAS or do not have cardiovascular risk factors may not benefit from this research.
What this research studies
This research investigates how per- and polyfluoroalkyl substances (PFAS), commonly found in everyday products, affect the health of blood vessels and contribute to cardiovascular diseases. By studying both human vascular responses and using mouse models, the research aims to uncover the mechanisms by which PFAS disrupt normal blood vessel function. Patients may be involved in understanding how these pollutants impact their health, particularly in relation to vascular conditions. The study will utilize advanced imaging techniques and physiological assays to gather data on the effects of PFAS on blood vessel behavior.
Why it matters
Potential benefit: If successful, this research could lead to better understanding and prevention strategies for cardiovascular diseases linked to environmental pollutants.
How similar studies have gone: Previous research has indicated that environmental pollutants can adversely affect cardiovascular health, suggesting that this investigation could yield significant insights.
Where this research is happening
-
Boston University Medical Campus
Boston, United States Active
Researchers
- Principal investigator: Gokce, Noyan — Boston University Medical Campus
- Study coordinator: Gokce, Noyan
About this research
- This is an active NIH-funded research project — typically early-stage science, not a clinical trial accepting patient enrollment.
- Some NIH-funded labs run parallel clinical studies or seek volunteers for related work. To check, contact the principal investigator or institution listed above.
- For full project details, budget, and progress reports, visit the official NIH RePORTER page.