Effects of fasting and exercise on fatigue in women with advanced breast cancer

Randomized Phase II Trial of Prolonged Overnight Fasting and/or Exercise on Fatigue and Other Patient Reported Outcomes in Women with Hormone Receptor Positive Advanced Breast Cancer (FastER)

NIH-funded research University of Miami School of Medicine · NIH-10932148

This study is looking at how skipping breakfast and exercising might help women with advanced breast cancer feel less tired and improve their quality of life, especially for those from diverse backgrounds facing unique challenges.

Quick facts

Grant typeR01 grant
Study typeNIH-funded research
Funding institutionUniversity of Miami School of Medicine NIH-funded
Lab location1 site (Coral Gables, United States)
Project IDNIH-10932148 on NIH RePORTER

What this research studies

This research investigates how prolonged overnight fasting and exercise can help reduce fatigue and improve quality of life for women with hormone receptor positive advanced breast cancer. Participants will be randomly assigned to different groups to assess the impact of these lifestyle interventions on their symptoms and overall well-being. The study aims to gather data from a diverse group of women, particularly focusing on those from underrepresented backgrounds who may experience unique challenges related to their treatment. By exploring these strategies, the research seeks to provide insights into effective ways to manage treatment-related fatigue.

Who could benefit from this research

Good fit: Ideal candidates for this research are women diagnosed with hormone receptor positive advanced breast cancer who are experiencing fatigue as a side effect of their treatment.

Not a fit: Patients with early-stage breast cancer or those not experiencing significant fatigue may not benefit from this research.

Why it matters

Potential benefit: If successful, this research could lead to improved management of fatigue and enhanced quality of life for women undergoing treatment for advanced breast cancer.

How similar studies have performed: Previous research has shown that lifestyle interventions like diet and exercise can improve fatigue in early-stage breast cancer, but this specific approach for advanced cases is still being explored.

Where this research is happening

Coral Gables, United States

Researchers

About this research

  1. This is an active NIH-funded research project — typically early-stage science, not a clinical trial accepting patient enrollment.
  2. Some NIH-funded labs run parallel clinical studies or seek volunteers for related work. To check, contact the principal investigator or institution listed above.
  3. For full project details, budget, and progress reports, visit the official NIH RePORTER page below.
Conditions Advanced CancerAffective Disorders
Last reviewed 2026-06-13 by the Find a Trial editorial team. Information on this page is for educational purposes and is not medical advice. Always consult qualified healthcare professionals about clinical trial participation.