Effects of a probiotic on blood vessel health and inflammation in people with type 2 diabetes
Impact of L. plantarum 299v supplementation on endothelial function and inflammation in humans with type 2 diabetes
This study is looking at whether a probiotic called Lactobacillus plantarum 299v can help improve blood vessel health and lower inflammation in people with type 2 diabetes, to see if it can support better overall health for managing their condition.
Quick facts
| Grant type | NIH-funded research |
|---|---|
| Study type | NIH-funded research |
| Funding institution | Medical College of Wisconsin NIH-funded |
| Lab location | 1 site (Milwaukee, United States) |
| Project ID | NIH-10992614 on NIH RePORTER |
What this research studies
This research investigates how the probiotic Lactobacillus plantarum 299v can improve blood vessel function and reduce inflammation in individuals with type 2 diabetes. The study aims to understand the potential benefits of this probiotic supplement on vascular health, which is crucial for preventing complications associated with diabetes. Participants will be monitored for changes in their endothelial function and inflammatory markers, providing insights into how dietary interventions can support their health. The research is designed to enhance the understanding of diabetes management through innovative approaches.
Who could benefit from this research
Good fit: Ideal candidates for this research are adults diagnosed with type 2 diabetes who are interested in exploring dietary supplements to improve their health.
Not a fit: Patients without a diagnosis of type 2 diabetes or those who are not interested in probiotic supplementation may not benefit from this research.
Why it matters
Potential benefit: If successful, this research could lead to new dietary recommendations that improve vascular health and reduce inflammation in patients with type 2 diabetes.
How similar studies have performed: Previous research has shown promising results with probiotics in improving metabolic health, suggesting that this approach may be beneficial for individuals with type 2 diabetes.
Where this research is happening
Milwaukee, United States
- Medical College of Wisconsin — Milwaukee, United States (Active)
Researchers
- Principal investigator: Widlansky, Michael E — Medical College of Wisconsin
- Study coordinator: Widlansky, Michael E
About this research
- This is an active NIH-funded research project — typically early-stage science, not a clinical trial accepting patient enrollment.
- Some NIH-funded labs run parallel clinical studies or seek volunteers for related work. To check, contact the principal investigator or institution listed above.
- For full project details, budget, and progress reports, visit the official NIH RePORTER page below.