Early palliative support by trained lay coaches for caregivers of people with advanced cancer

Lay Coach-led Early Palliative Care for Underserved Advanced Cancer Caregivers

NIH-funded research University of Alabama at Birmingham · NIH-11044561

This program offers early palliative support from trained lay coaches to help under-resourced family and friend caregivers of people newly diagnosed with advanced cancer.

Quick facts

Grant typeR37 grant
Study typeNIH-funded research
Funding institutionUniversity of Alabama at Birmingham NIH-funded
Lab location1 site (Birmingham, United States)
Project IDNIH-11044561 on NIH RePORTER

What this research studies

If you are a family or friend caring for someone with newly diagnosed advanced cancer, this program gives six structured coaching sessions plus monthly follow-up from diagnosis through early bereavement. Trained lay navigators provide practical help with stress management, coping, caregiving skills, help-seeking, and decision-making. The work builds on the ENABLE Cornerstone model and is being carried out within a randomized trial that also tracks longer-term caregiver distress, quality of life, healthcare use, and bereavement outcomes. The project also looks at how the program can be delivered and used in real-world care settings.

Who could benefit from this research

Good fit: Ideal candidates are adult (21+) family or friend caregivers of adults newly diagnosed with advanced cancer, especially those from historically under-resourced backgrounds with limited supports.

Not a fit: Caregivers of patients without advanced cancer, paid professional caregivers, or people already receiving comprehensive palliative care supports may be less likely to benefit from this specific program.

Why it matters

Potential benefit: If successful, the program could lower caregiver distress, improve caregiver quality of life, support better decision-making, and potentially reduce unnecessary healthcare use for patients near the end of life.

How similar studies have performed: Earlier palliative care programs, including prior ENABLE trials, have shown benefits for patients and caregivers, though lay coach-led early models with extended follow-up for under-resourced groups are less commonly tested.

Where this research is happening

Birmingham, United States

Researchers

About this research

  1. This is an active NIH-funded research project — typically early-stage science, not a clinical trial accepting patient enrollment.
  2. Some NIH-funded labs run parallel clinical studies or seek volunteers for related work. To check, contact the principal investigator or institution listed above.
  3. For full project details, budget, and progress reports, visit the official NIH RePORTER page below.
Conditions Advanced Cancer
Last reviewed 2026-06-13 by the Find a Trial editorial team. Information on this page is for educational purposes and is not medical advice. Always consult qualified healthcare professionals about clinical trial participation.