Early brain activity and parenting linked to infant anxiety risk

Precursors of Anxiety: The Role of Lateralized Brain Activation and Maternal Sensitivity

NIH-funded research Washington State University · NIH-11505549

This project looks at how infants' early brain activity and mothers' sensitivity relate to fear behavior and later anxiety risk.

Quick facts

Grant typeR01 grant
Study typeNIH-funded research
Funding institutionWashington State University NIH-funded
Lab location1 site (Pullman, United States)
Project IDNIH-11505549 on NIH RePORTER

What this research studies

You and your baby would join regular visits where researchers record your baby's brain activity with EEG, observe fearful behaviors, and collect information about parenting and sensitivity. The team follows changes in left and right frontal brain activation across infancy and compares those shifts with how the baby's fearfulness develops. They also test whether more sensitive caregiving changes how brain patterns connect to anxiety risk. The study follows infants over time to identify early markers tied to later anxiety symptoms.

Who could benefit from this research

Good fit: Ideal candidates are infants in their first year of life and their mothers or primary caregivers who can attend in-person EEG and behavioral visits and complete questionnaires.

Not a fit: Adults with long-standing anxiety or people outside the infant age range are unlikely to receive direct benefit from this work.

Why it matters

Potential benefit: If successful, this could help identify infants at higher risk for anxiety earlier and point to parenting-focused strategies to reduce that risk.

How similar studies have performed: Previous studies have linked fearful temperament and right-frontal EEG patterns to later anxiety, but following dynamic hemispheric changes together with maternal sensitivity across infancy is relatively new.

Where this research is happening

Pullman, United States

Researchers

About this research

  1. This is an active NIH-funded research project — typically early-stage science, not a clinical trial accepting patient enrollment.
  2. Some NIH-funded labs run parallel clinical studies or seek volunteers for related work. To check, contact the principal investigator or institution listed above.
  3. For full project details, budget, and progress reports, visit the official NIH RePORTER page below.
Conditions Anxiety Disorders
Last reviewed 2026-06-13 by the Find a Trial editorial team. Information on this page is for educational purposes and is not medical advice. Always consult qualified healthcare professionals about clinical trial participation.