NIH-funded research Career grant

Digital tool to help breast cancer survivors stick to hormone therapy

Official title: Developing a digital symptom monitoring intervention to improve adherence to endocrine therapy among breast cancer survivors

Funded at University of Pennsylvania · NIH-11417149 · Data updated 2026-11-12

A patient-friendly digital program is being developed to help women with breast cancer take their prescribed hormone therapy more consistently.

More Breast Cancer research and trials

Quick facts

Grant typeCareer grant
Study typeNIH-funded research
Funding institutionUniversity of Pennsylvania
NIH-funded
Lab location1 site (Philadelphia, United States)
Project startSeptember 18, 2023
Project endAugust 31, 2028
Funding year2026
Award (this year)$284,901
NIH project number5K08CA279076-04
Project IDNIH-11417149 on NIH RePORTER

Who could benefit from this research

Could help

Ideal candidates are women with non-metastatic hormone receptor-positive breast cancer on endocrine therapy who experience symptom burden.

Less likely to help

Patients not on endocrine therapy or those without symptom-related barriers may see limited benefit.

What this research studies

If you have non-metastatic breast cancer and are on hormone therapy, this project will create and test an online intervention designed with input from survivors. The team will focus on monitoring symptoms and teaching self-management to support adherence and quality of life. They will start by refining the tool with feedback, then test whether it is acceptable, feasible, and shows any signs of improving adherence and reducing symptoms.

Why it matters

Potential benefit: If successful, the intervention could help more patients stay on therapy and feel better while reducing cancer recurrence risk.

How similar studies have gone: Previous attempts had modest short-term gains, but this project aims to tailor to those at high risk of nonadherence.

Where this research is happening

  • University of Pennsylvania
    Philadelphia, United States
    Active

Researchers

  • Principal investigator: Lee, Kimberley T — University of Pennsylvania
  • Study coordinator: Lee, Kimberley T

Related research

Other NIH-funded projects on the same topics.

About this research

  1. This is an active NIH-funded research project — typically early-stage science, not a clinical trial accepting patient enrollment.
  2. Some NIH-funded labs run parallel clinical studies or seek volunteers for related work. To check, contact the principal investigator or institution listed above.
  3. For full project details, budget, and progress reports, visit the official NIH RePORTER page.
Last reviewed 2026-11-14 by the Find a Trial editorial team. Information on this page is for educational purposes and is not medical advice. Always consult qualified healthcare professionals about clinical trial participation.