NIH-funded research R01 grant

Digital biomarkers from wearables for cardiovascular health

Official title: Digital biomarker discovery with multimodal and longitudinal wearable data using novel functional and distributional data analysis methods

Funded at University of South Carolina at Columbia · NIH-11422149 · Data updated 2026-11-12

A researcher will develop new ways to read and combine data from wearable sensors (like heart rate, activity, and glucose monitors) to better understand heart and brain health in people.

Quick facts

Grant typeR01 grant
Study typeNIH-funded research
Funding institutionUniversity of South Carolina at Columbia
NIH-funded
Lab location1 site (Columbia, United States)
Project startSeptember 5, 2026
Project endMay 31, 2031
Funding year2026
Award (this year)$649,041
NIH project number1R01HL187193-01
Project IDNIH-11422149 on NIH RePORTER

Who could benefit from this research

Could help

Individuals with cardiovascular conditions or related health concerns who use wearable sensors in daily life.

Less likely to help

People not using wearables or without cardiovascular/neurological symptoms may see limited direct benefit.

What this research studies

This project uses wearable devices to collect continuous physiological data in real life, then creates new statistical methods to capture how these signals vary over time and across distributions. By combining functional data analysis with distributional data analysis, it aims to identify digital phenotypes that reflect cardiovascular and cognitive health. The work will help translate big sensor data into meaningful patterns that could track disease progression and personalize monitoring. It focuses on people wearing sensors in everyday settings, with the goal of making digital health signals more informative for clinicians and patients.

Why it matters

Potential benefit: If successful, the methods could improve early detection and monitoring of cardiovascular and cognitive changes using everyday wearables.

How similar studies have gone: Previous studies show promise for wearable data in health monitoring, but this project advances novel methods integrating multiple data types.

Where this research is happening

  • University of South Carolina at Columbia
    Columbia, United States
    Active

Researchers

  • Principal investigator: Ghosal, Rahul — University of South Carolina at Columbia
  • Study coordinator: Ghosal, Rahul

About this research

  1. This is an active NIH-funded research project — typically early-stage science, not a clinical trial accepting patient enrollment.
  2. Some NIH-funded labs run parallel clinical studies or seek volunteers for related work. To check, contact the principal investigator or institution listed above.
  3. For full project details, budget, and progress reports, visit the official NIH RePORTER page.
Last reviewed 2026-11-14 by the Find a Trial editorial team. Information on this page is for educational purposes and is not medical advice. Always consult qualified healthcare professionals about clinical trial participation.