Diabetic foot ulcer data and coordination center
Official title: University of Michigan Data Coordinating Center for the Diabetic Foot Consortium
Funded at University of Michigan at Ann Arbor · NIH-11290368 · Data updated 2026-11-12
This center brings clinics and labs together to find blood and wound markers that help predict healing and prevent repeat foot ulcers in people with diabetes.
Quick facts
| Grant type | NIH-funded research |
|---|---|
| Study type | NIH-funded research |
| Funding institution | University of Michigan at Ann Arbor NIH-funded |
| Lab location | 1 site (Ann Arbor, United States) |
| Project start | July 1, 2019 |
| Project end | December 31, 2027 |
| Funding year | 2026 |
| Award (this year) | $3,305,818 |
| NIH project number | 5U24DK122927-08 |
| Project ID | NIH-11290368 on NIH RePORTER |
Who could benefit from this research
✓Could help
Ideal candidates are adults with diabetes who have an active or recently healed foot ulcer or a history of recurrent diabetic foot ulcers and who can attend a participating clinic.
✕Less likely to help
People without diabetes or without current or recent diabetic foot ulcers, or those unable to attend participating clinic sites, are unlikely to benefit directly.
What this research studies
If you join work supported by this center, clinics will collect health information and blood/wound samples from people with diabetes and foot ulcers. The data coordinating center organizes those records and specimens, runs statistical analyses, and helps validate biomarkers across several clinic sites. Teams across hospitals and labs compare results to find consistent tests and keep a biorepository of samples for future studies. The coordinated effort also looks at how patient and doctor factors relate to better or worse healing outcomes.
Why it matters
Potential benefit: If successful, this work could lead to tests that predict which ulcers will heal and guide treatments to reduce re-ulceration.
How similar studies have gone: Previous smaller studies have suggested promising biomarkers but few have been validated across multiple sites, so this multi-site validation is a needed next step.
Where this research is happening
-
University of Michigan at Ann Arbor
Ann Arbor, United States Active
Researchers
- Principal investigator: Spino, Catherine a — University of Michigan at Ann Arbor
- Study coordinator: Spino, Catherine a
Related research
Other NIH-funded projects on the same topics.
-
Improving Diabetic Foot Ulcer Offloading with User-Friendly Cast Walker Design
A small pilot study to see how different removable cast walker designs affect daily use and healing of diabetic foot ulcers.
-
Home-based exercise to help Veterans recover after healed diabetic foot ulcers
A home-based exercise program for Veterans who recently healed from a diabetic foot ulcer to improve walking and daily function.
-
How Medicaid Coverage Changes Diabetic Foot Care in Safety-Net Patients
This project looks at how new Medicaid coverage in California affects foot care, ED visits, and outcomes for adults with diabetes in safety-net populations.
-
Multi-targeted approach to help heal diabetic foot ulcers using electric fields and nitric oxide
A study to test a combo treatment using electric field stimulation and nitric oxide to boost healing in diabetic foot ulcers.
-
Wound fluid test to predict healing in diabetic foot ulcers
This project looks for chemical signals in the fluid from diabetic foot ulcers that could tell adults with diabetes whether a wound will heal with standard care or need a different treatment.
-
MTX-001 for healing diabetic foot ulcers in people with diabetes
A first–in–class biologic therapy called MTX-001 is being tested to help heal diabetic foot ulcers and reduce infection risk in adults with diabetes.
About this research
- This is an active NIH-funded research project — typically early-stage science, not a clinical trial accepting patient enrollment.
- Some NIH-funded labs run parallel clinical studies or seek volunteers for related work. To check, contact the principal investigator or institution listed above.
- For full project details, budget, and progress reports, visit the official NIH RePORTER page.