Developing vaccines to prevent future pandemics from certain viruses

Antibody, Epitope and Machine Learning Core

NIH-funded research University of California-Irvine · NIH-10863341

This study is working on developing new vaccines to protect us from future viruses that could cause pandemics, using smart computer techniques to understand how these viruses might change and how our immune system can fight them.

Quick facts

Grant typeNIH-funded research
Study typeNIH-funded research
Funding institutionUniversity of California-Irvine NIH-funded
Lab location1 site (Irvine, United States)
Project IDNIH-10863341 on NIH RePORTER

What this research studies

This research focuses on creating vaccine candidates against viruses that could cause future pandemics, specifically from the bunyavirus, paramyxovirus, and picornavirus families. It employs advanced computational techniques and machine learning to identify and map viral epitopes, which are crucial for vaccine and antibody design. By predicting how these viruses may evolve and how the immune system responds to them, the project aims to enhance the effectiveness of vaccines and antibodies. This work will also provide essential tools for tracking viral evolution and improving public health responses.

Who could benefit from this research

Good fit: Ideal candidates for this research include individuals at risk of exposure to emerging viral infections or those interested in contributing to vaccine development efforts.

Not a fit: Patients who are not at risk for viral infections or those who do not wish to participate in vaccine-related research may not benefit from this research.

Why it matters

Potential benefit: If successful, this research could lead to the development of effective vaccines that prevent future viral pandemics, ultimately saving lives.

How similar studies have performed: Other research has shown promise in using machine learning and epitope mapping for vaccine development, indicating a strong potential for success in this approach.

Where this research is happening

Irvine, United States

Researchers

About this research

  1. This is an active NIH-funded research project — typically early-stage science, not a clinical trial accepting patient enrollment.
  2. Some NIH-funded labs run parallel clinical studies or seek volunteers for related work. To check, contact the principal investigator or institution listed above.
  3. For full project details, budget, and progress reports, visit the official NIH RePORTER page below.
Conditions Acquired Immune Deficiency Syndrome VirusAcquired Immunodeficiency Syndrome Virus
Last reviewed 2026-06-09 by the Find a Trial editorial team. Information on this page is for educational purposes and is not medical advice. Always consult qualified healthcare professionals about clinical trial participation.