Developing treatments for enterovirus infections in children

ADVANCEMENT OF POTENT BROAD SPECTRUM ENTEROVIRUS THERAPEUTICS

NIH-funded research Integrated Research Associates, LLC · NIH-10684969

This study is working on developing new treatments to help young children who get sick from enteroviruses, which can lead to serious conditions like acute flaccid myelitis and Hand Foot and Mouth Disease, since there aren’t many approved medicines or vaccines for these illnesses right now.

Quick facts

Grant typeNIH-funded research
Study typeNIH-funded research
Funding institutionIntegrated Research Associates, LLC NIH-funded
Lab location1 site (San Rafael, United States)
Project IDNIH-10684969 on NIH RePORTER

What this research studies

This research focuses on creating broad-spectrum monoclonal antibodies to combat enteroviruses, which are known to cause serious neurological diseases in young children, such as acute flaccid myelitis and Hand Foot and Mouth Disease. The project aims to address the lack of approved therapeutics and vaccines for these viruses in the United States. By targeting these pathogens, the research seeks to provide effective treatment options for affected children and potentially prevent severe outcomes associated with these infections.

Who could benefit from this research

Good fit: Ideal candidates for this research are young children, particularly those under 11 years old, who are at risk of enterovirus infections.

Not a fit: Patients who are adults or those with enterovirus infections that do not lead to neurological complications may not benefit from this research.

Why it matters

Potential benefit: If successful, this research could provide effective treatments for enterovirus infections, significantly improving health outcomes for affected children.

How similar studies have performed: While there has been limited success in developing treatments for enteroviruses, this approach of using monoclonal antibodies is relatively novel and has not been extensively tested in this context.

Where this research is happening

San Rafael, United States

Researchers

About this research

  1. This is an active NIH-funded research project — typically early-stage science, not a clinical trial accepting patient enrollment.
  2. Some NIH-funded labs run parallel clinical studies or seek volunteers for related work. To check, contact the principal investigator or institution listed above.
  3. For full project details, budget, and progress reports, visit the official NIH RePORTER page below.
Conditions Hand, Foot and Mouth DiseaseNervous System DiseasesNeurologic DisordersNeurological Disordersneurological disease
Last reviewed 2026-06-13 by the Find a Trial editorial team. Information on this page is for educational purposes and is not medical advice. Always consult qualified healthcare professionals about clinical trial participation.