Developing tools to improve drug development for various diseases
Official title: A Translational Center for Barrier MPS
Funded at University of Rochester · NIH-11005753 · Data updated 2026-11-12
This study is working on new tools to help create better medicines by understanding how the body's barriers affect diseases like brain disorders, autoimmune issues, and infections, so that patients can have more effective treatment options in the future.
Quick facts
| Grant type | NIH-funded research |
|---|---|
| Study type | NIH-funded research |
| Funding institution | University of Rochester NIH-funded |
| Lab location | 1 site (Rochester, United States) |
| Project start | January 15, 2024 |
| Project end | December 31, 2028 |
| Funding year | 2025 |
| Award (this year) | $1,507,855 |
| NIH project number | 5U2CAG088071-02 |
| Project ID | NIH-11005753 on NIH RePORTER |
Who could benefit from this research
✓Could help
Ideal candidates for this research are individuals suffering from central nervous system disorders, autoimmune diseases, or those at risk of sepsis.
✕Less likely to help
Patients with conditions unrelated to the focus areas of this research may not receive any benefit.
What this research studies
This research focuses on creating innovative drug development tools that assess how barrier functions in the body affect diseases, injuries, and infections. The project aims to develop and validate these tools for conditions such as central nervous system disorders, autoimmune diseases, and sepsis. By utilizing advanced models and technologies, the research team will ensure that these tools are reliable and effective for clinical use. Patients may benefit from improved treatment options as these tools help streamline the drug development process.
Why it matters
Potential benefit: If successful, this research could lead to more effective treatments for patients with serious conditions like autoimmune diseases and central nervous system disorders.
How similar studies have gone: Previous research has shown promise in developing drug development tools for similar conditions, indicating a potential for success in this approach.
Where this research is happening
-
University of Rochester
Rochester, United States Active
Researchers
- Principal investigator: Mcgrath, James L — University of Rochester
- Study coordinator: Mcgrath, James L
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About this research
- This is an active NIH-funded research project — typically early-stage science, not a clinical trial accepting patient enrollment.
- Some NIH-funded labs run parallel clinical studies or seek volunteers for related work. To check, contact the principal investigator or institution listed above.
- For full project details, budget, and progress reports, visit the official NIH RePORTER page.