Developing tools to help doctors prevent tuberculosis in children and adolescents.
Official title: Tools to facilitate preventive therapy for children and adolescents in primary care.
Funded at Socios En Salud Sucursal Peru · NIH-10784569 · Data updated 2026-11-12
This study is looking to help doctors better protect children and teens who have been around someone with tuberculosis (TB) by creating a simple way to figure out who needs more tests and who can start treatment right away, while also testing a computer program that helps spot TB on chest X-rays.
Quick facts
| Grant type | R03 grant |
|---|---|
| Study type | NIH-funded research |
| Funding institution | Socios En Salud Sucursal Peru NIH-funded |
| Lab location | 1 site (Lima, Peru) |
| Project start | September 1, 2024 |
| Project end | August 31, 2026 |
| Funding year | 2024 |
| Award (this year) | $106,318 |
| NIH project number | 1R03HD113830-01 |
| Project ID | NIH-10784569 on NIH RePORTER |
Who could benefit from this research
✓Could help
Ideal candidates for this research are children and adolescents under 21 years old who have been exposed to tuberculosis in their households.
✕Less likely to help
Patients who are not household contacts of tuberculosis or those over 21 years old may not benefit from this research.
What this research studies
This research focuses on improving the prevention of tuberculosis (TB) in children and adolescents who have been exposed to the disease in their homes. It aims to create a risk score that helps primary care physicians identify which young patients need further evaluation for active TB and which can start preventive treatment right away. Additionally, the study will assess the effectiveness of computer-aided detection software to analyze chest X-rays for TB abnormalities in these young patients. By enhancing diagnostic capabilities in low-resource settings, the research seeks to improve health outcomes for vulnerable populations.
Why it matters
Potential benefit: If successful, this research could significantly reduce the incidence of active tuberculosis in children and adolescents by enabling timely preventive treatment.
How similar studies have gone: Previous research has shown promise in using risk scores and computer-aided detection for improving TB diagnosis, indicating that this approach could be effective.
Where this research is happening
-
Socios En Salud Sucursal Peru
Lima, Peru Active
Researchers
- Principal investigator: Puma, Daniela — Socios En Salud Sucursal Peru
- Study coordinator: Puma, Daniela
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About this research
- This is an active NIH-funded research project — typically early-stage science, not a clinical trial accepting patient enrollment.
- Some NIH-funded labs run parallel clinical studies or seek volunteers for related work. To check, contact the principal investigator or institution listed above.
- For full project details, budget, and progress reports, visit the official NIH RePORTER page.