Developing tools for analyzing genetic data from eukaryotic pathogens
Data and analysis ecosystem for eukaryotic pathogen targeted sequencing
This study is working on new software to help scientists better understand the genetic information of certain germs that can make people sick, like viruses and parasites, so that we can improve treatments and learn how these germs spread and resist medicines.
Quick facts
| Grant type | U01 cooperative agreement |
|---|---|
| Study type | NIH-funded research |
| Funding institution | University of California, San Francisco NIH-funded |
| Lab location | 1 site (San Francisco, United States) |
| Project ID | NIH-11123462 on NIH RePORTER |
What this research studies
This research focuses on creating advanced software and computational tools to analyze genomic data from eukaryotic pathogens, which include complex organisms like certain viruses and parasites. By addressing the unique challenges posed by these pathogens, such as their larger genomes and complicated transmission dynamics, the project aims to improve the accuracy and reproducibility of genomic analyses. Patients may benefit from enhanced understanding of pathogen evolution, transmission patterns, and drug resistance, ultimately leading to better treatment strategies. The research will involve developing bioinformatics pipelines and data standards to facilitate the sharing and analysis of genomic data.
Who could benefit from this research
Good fit: Ideal candidates for participation or benefit include individuals affected by infections from eukaryotic pathogens, such as those with AIDS or Chagas disease.
Not a fit: Patients with bacterial or viral infections that do not involve eukaryotic pathogens may not receive direct benefits from this research.
Why it matters
Potential benefit: If successful, this research could lead to improved diagnostic and treatment options for infections caused by eukaryotic pathogens.
How similar studies have performed: Other research has shown success in developing genomic analysis tools for simpler organisms, but this approach for eukaryotic pathogens is relatively novel.
Where this research is happening
San Francisco, United States
- University of California, San Francisco — San Francisco, United States (Active)
Researchers
- Principal investigator: Greenhouse, Bryan R — University of California, San Francisco
- Study coordinator: Greenhouse, Bryan R
About this research
- This is an active NIH-funded research project — typically early-stage science, not a clinical trial accepting patient enrollment.
- Some NIH-funded labs run parallel clinical studies or seek volunteers for related work. To check, contact the principal investigator or institution listed above.
- For full project details, budget, and progress reports, visit the official NIH RePORTER page below.