Developing non-invasive tests to assess retinal function

Non-Invasive Functional Assessments for Translational Retinal Therapeutics

NIH-funded research Marquette University · NIH-10654125

This study is working on new, gentle ways to check how well the light-sensitive cells in your eyes are working, using tree shrews to help develop these methods, which could improve how we understand and treat vision problems.

Quick facts

Grant typeR15 grant
Study typeNIH-funded research
Funding institutionMarquette University NIH-funded
Lab location1 site (Milwaukee, United States)
Project IDNIH-10654125 on NIH RePORTER

What this research studies

This research focuses on creating non-invasive tools to evaluate the function of photoreceptors, which are essential for vision. By using a tree shrew model, the study aims to develop techniques that can measure the functional signals of photoreceptors without invasive procedures. The researchers will enhance the reliability and efficiency of these imaging methods and validate them against established measurements of retinal function. This approach could lead to better assessments of therapies aimed at restoring vision.

Who could benefit from this research

Good fit: Ideal candidates for this research are individuals experiencing vision loss due to retinal diseases or injuries affecting photoreceptors.

Not a fit: Patients with conditions unrelated to photoreceptor dysfunction or those who do not have access to the specific imaging technologies may not benefit from this research.

Why it matters

Potential benefit: If successful, this research could provide new ways to monitor and evaluate treatments for vision impairment caused by photoreceptor dysfunction.

How similar studies have performed: While there has been significant research on photoreceptor function, the specific non-invasive techniques proposed in this study are novel and have not been extensively tested.

Where this research is happening

Milwaukee, United States

Researchers

About this research

  1. This is an active NIH-funded research project — typically early-stage science, not a clinical trial accepting patient enrollment.
  2. Some NIH-funded labs run parallel clinical studies or seek volunteers for related work. To check, contact the principal investigator or institution listed above.
  3. For full project details, budget, and progress reports, visit the official NIH RePORTER page below.
Last reviewed 2026-06-09 by the Find a Trial editorial team. Information on this page is for educational purposes and is not medical advice. Always consult qualified healthcare professionals about clinical trial participation.