Developing non-invasive sensors to monitor autoimmune diseases like multiple sclerosis
Immulogical Niches and Non-invasive Biosensors for Autoimmune Monitoring
This study is working on a new way to keep an eye on multiple sclerosis by creating a special sensor that can track your immune system's activity without needing painful tests, helping to better understand how the disease is changing over time.
Quick facts
| Grant type | NIH-funded research |
|---|---|
| Study type | NIH-funded research |
| Funding institution | University of Michigan at Ann Arbor NIH-funded |
| Lab location | 1 site (Ann Arbor, United States) |
| Project ID | NIH-10851878 on NIH RePORTER |
What this research studies
This research focuses on creating a new method to monitor multiple sclerosis, an autoimmune disease characterized by unpredictable relapses and remissions. The approach involves developing an immunological niche within the body that can reflect immune responses related to the central nervous system. By using tissue engineering principles, the researchers aim to implant non-invasive sensors that can continuously monitor immune activity and disease progression without the need for painful biopsies. The study will utilize advanced techniques such as gene expression analysis and machine learning to identify disease markers.
Who could benefit from this research
Good fit: Ideal candidates for this research are individuals diagnosed with multiple sclerosis who experience unpredictable disease activity.
Not a fit: Patients with other autoimmune diseases or those who do not have multiple sclerosis may not benefit from this research.
Why it matters
Potential benefit: If successful, this research could lead to better monitoring and management of multiple sclerosis, potentially reducing the frequency of relapses and improving patient outcomes.
How similar studies have performed: Previous research has shown promise in using biosensors and tissue engineering for monitoring autoimmune conditions, indicating potential success for this novel approach.
Where this research is happening
Ann Arbor, United States
- University of Michigan at Ann Arbor — Ann Arbor, United States (Active)
Researchers
- Principal investigator: Morris, Aaron Harvey — University of Michigan at Ann Arbor
- Study coordinator: Morris, Aaron Harvey
About this research
- This is an active NIH-funded research project — typically early-stage science, not a clinical trial accepting patient enrollment.
- Some NIH-funded labs run parallel clinical studies or seek volunteers for related work. To check, contact the principal investigator or institution listed above.
- For full project details, budget, and progress reports, visit the official NIH RePORTER page below.