NIH-funded research NIH-funded research

Developing new ways to monitor autoimmune diseases like multiple sclerosis.

Official title: Supplement to Immunological Niches and Noninvasive Biosensors for Autoimmune Monitoring

Funded at University of Michigan at Ann Arbor · NIH-11237848 · Data updated 2026-11-12

This study is looking at new ways to keep an eye on multiple sclerosis by using special tools that can track how your immune system is working in real-time, which could help doctors create better, personalized treatments just for you.

Quick facts

Grant typeNIH-funded research
Study typeNIH-funded research
Funding institutionUniversity of Michigan at Ann Arbor
NIH-funded
Lab location1 site (Ann Arbor, United States)
Project startJanuary 1, 2025
Project endMay 31, 2026
Funding year2025
Award (this year)$94,265
NIH project number3R00EB028840-05S2
Project IDNIH-11237848 on NIH RePORTER

Who could benefit from this research

Could help

Ideal candidates for this research are individuals diagnosed with multiple sclerosis or other autoimmune diseases.

Less likely to help

Patients with autoimmune conditions that do not involve the adaptive immune response may not benefit from this research.

What this research studies

This research focuses on improving the monitoring of multiple sclerosis (MS), an autoimmune disease known for its unpredictable relapses. The approach involves creating engineered immunological niches and biosensors that can detect immune responses in real-time without the need for invasive biopsies. By using tissue engineering and synthetic biology, the researchers aim to track the behavior of immune cells and cytokines in the body, which could lead to better management of the disease. Patients may benefit from more effective treatments that can be tailored based on their specific immune responses.

Why it matters

Potential benefit: If successful, this research could lead to improved monitoring and management of multiple sclerosis, potentially reducing relapse rates and disease progression.

How similar studies have gone: Previous research has shown promise in using biosensors and tissue engineering for monitoring immune responses, indicating a potential for success in this novel approach.

Where this research is happening

  • University of Michigan at Ann Arbor
    Ann Arbor, United States
    Active

Researchers

  • Principal investigator: Morris, Aaron Harvey — University of Michigan at Ann Arbor
  • Study coordinator: Morris, Aaron Harvey

About this research

  1. This is an active NIH-funded research project — typically early-stage science, not a clinical trial accepting patient enrollment.
  2. Some NIH-funded labs run parallel clinical studies or seek volunteers for related work. To check, contact the principal investigator or institution listed above.
  3. For full project details, budget, and progress reports, visit the official NIH RePORTER page.
Last reviewed 2026-11-14 by the Find a Trial editorial team. Information on this page is for educational purposes and is not medical advice. Always consult qualified healthcare professionals about clinical trial participation.