Developing new methods to create complex molecules for potential drug development
Official title: Supplement: Studies in the Synthesis of Complex Organic Molecules with Donor-Donor Carbenes
Funded at University of California at Davis · NIH-11029481 · Data updated 2026-11-12
This study is looking at new ways to quickly make complex molecules that could help create new medicines for treating various diseases, making it easier to find drug options that aren't currently available.
Quick facts
| Grant type | NIH-funded research |
|---|---|
| Study type | NIH-funded research |
| Funding institution | University of California at Davis NIH-funded |
| Lab location | 1 site (Davis, United States) |
| Project start | September 1, 2023 |
| Project end | June 30, 2028 |
| Funding year | 2024 |
| Award (this year) | $117,591 |
| NIH project number | 3R35GM149209-02S1 |
| Project ID | NIH-11029481 on NIH RePORTER |
Who could benefit from this research
✓Could help
Ideal candidates for benefiting from this research include individuals suffering from acute and chronic diseases that currently lack effective treatment options.
✕Less likely to help
Patients with conditions that are already well-managed by existing therapies may not see significant benefits from this research.
What this research studies
This research focuses on creating innovative synthetic methods to rapidly prepare complex organic molecules that could lead to new drug discoveries. By exploring the reactivity of rhodium donor-donor carbenes, the project aims to unlock new chemical reactions that can produce useful compounds. The researchers will investigate how these carbenes can be utilized in various applications, particularly in creating small molecules that are essential for treating both acute and chronic diseases. The ultimate goal is to enhance the accessibility of novel drug candidates that are not currently available due to patent restrictions.
Why it matters
Potential benefit: If successful, this research could lead to the development of new drugs that improve treatment options for various diseases.
How similar studies have gone: Previous research has shown promise in developing new synthetic methods for drug discovery, indicating that this approach could yield significant advancements.
Where this research is happening
-
University of California at Davis
Davis, United States Active
Researchers
- Principal investigator: Shaw, Jared Thomas — University of California at Davis
- Study coordinator: Shaw, Jared Thomas
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About this research
- This is an active NIH-funded research project — typically early-stage science, not a clinical trial accepting patient enrollment.
- Some NIH-funded labs run parallel clinical studies or seek volunteers for related work. To check, contact the principal investigator or institution listed above.
- For full project details, budget, and progress reports, visit the official NIH RePORTER page.