Developing new cancer models from diverse populations
Official title: University of California and UT Southwestern D-PDTC
Funded at University of California at Davis · NIH-10896233 · Data updated 2026-11-12
This study is looking to create new cancer models from diverse patients, especially Asian women, to help us learn more about cancer and see how well current treatments work, and you can help by providing samples if you're interested!
Quick facts
| Grant type | NIH-funded research |
|---|---|
| Study type | NIH-funded research |
| Funding institution | University of California at Davis NIH-funded |
| Lab location | 1 site (Davis, United States) |
| Project start | August 1, 2023 |
| Project end | July 31, 2028 |
| Funding year | 2024 |
| Award (this year) | $993,582 |
| NIH project number | 5U54CA283766-02 |
| Project ID | NIH-10896233 on NIH RePORTER |
Who could benefit from this research
✓Could help
Ideal candidates for participation include Asian females with advanced cancer who are seeking innovative treatment options.
✕Less likely to help
Patients with non-advanced cancer or those outside the targeted demographic may not benefit from this research.
What this research studies
This research focuses on creating and characterizing at least 120 new patient-derived xenografts (PDXs) from racially and ethnically diverse populations, particularly Asian females. By using these PDXs as preclinical models, the research aims to better understand how cancer develops and to evaluate the effectiveness of existing FDA-approved and NCI-CTEP therapies. The project involves collaboration among several leading cancer centers and utilizes advanced bioinformatics and clinical trial methodologies to address cancer health disparities. Patients may have the opportunity to contribute to this important work by providing samples for the development of these models.
Why it matters
Potential benefit: If successful, this research could lead to more effective cancer treatments tailored to diverse populations.
How similar studies have gone: Previous research has shown success in using patient-derived xenografts to study cancer, making this approach promising yet focused on enhancing diversity.
Where this research is happening
-
University of California at Davis
Davis, United States Active
Researchers
- Principal investigator: Carvajal Carmona, Luis Guillermo — University of California at Davis
- Study coordinator: Carvajal Carmona, Luis Guillermo
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About this research
- This is an active NIH-funded research project — typically early-stage science, not a clinical trial accepting patient enrollment.
- Some NIH-funded labs run parallel clinical studies or seek volunteers for related work. To check, contact the principal investigator or institution listed above.
- For full project details, budget, and progress reports, visit the official NIH RePORTER page.