Developing new antiviral treatments for Zika and Dengue viruses
Anchimerically Activatable Anti-Zika/Dengue ProTides
This study is working on new antiviral medicines to help people with Zika and Dengue viruses by using special compounds that could make treatments more effective and easier to use.
Quick facts
| Grant type | R01 grant |
|---|---|
| Study type | NIH-funded research |
| Funding institution | University of Minnesota NIH-funded |
| Lab location | 1 site (Minneapolis, United States) |
| Project ID | NIH-10891577 on NIH RePORTER |
What this research studies
This research focuses on creating new antiviral medications specifically targeting the Zika and Dengue viruses, which are responsible for severe health issues worldwide. The approach involves using innovative compounds known as ProTides, which have shown promise in treating other viral infections. By activating these compounds through a specific biochemical process, the research aims to develop effective therapies that could alleviate the symptoms and complications associated with these viral infections. Patients may benefit from these new treatments, especially since current options are limited.
Who could benefit from this research
Good fit: Ideal candidates for this research include individuals who have been diagnosed with Zika or Dengue virus infections or are at high risk of contracting these viruses.
Not a fit: Patients who are not infected with Zika or Dengue viruses or those who have other unrelated health conditions may not benefit from this research.
Why it matters
Potential benefit: If successful, this research could lead to effective antiviral treatments for Zika and Dengue virus infections, potentially reducing severe health outcomes.
How similar studies have performed: Previous research has successfully developed antiviral treatments using similar ProTide approaches, indicating potential for success in this area.
Where this research is happening
Minneapolis, United States
- University of Minnesota — Minneapolis, United States (Active)
Researchers
- Principal investigator: Wagner, Carston R. — University of Minnesota
- Study coordinator: Wagner, Carston R.
About this research
- This is an active NIH-funded research project — typically early-stage science, not a clinical trial accepting patient enrollment.
- Some NIH-funded labs run parallel clinical studies or seek volunteers for related work. To check, contact the principal investigator or institution listed above.
- For full project details, budget, and progress reports, visit the official NIH RePORTER page below.