Developing models to understand infectious diseases.
Official title: Pre-Clinical Models of Infectious Diseases
Funded at Pennsylvania State Univ Hershey Med Ctr · NIH-11197645 · Data updated 2026-11-12
This study is working on building models that mimic infectious diseases to help us learn how they work and find better treatments, which could lead to new options for patients dealing with infections.
Quick facts
| Grant type | NIH-funded research |
|---|---|
| Study type | NIH-funded research |
| Funding institution | Pennsylvania State Univ Hershey Med Ctr NIH-funded |
| Lab location | 1 site (Hershey, United States) |
| Project start | July 15, 2024 |
| Project end | July 14, 2031 |
| Funding year | 2024 |
| Award (this year) | $2,500 |
| NIH project number | 75N93024D00024-0-759302400001-1 |
| Project ID | NIH-11197645 on NIH RePORTER |
Who could benefit from this research
✓Could help
Ideal candidates for this research are individuals at risk of infectious diseases or those who may benefit from new medical countermeasures.
✕Less likely to help
Patients with non-infectious diseases or those who are not at risk for infections may not receive any benefit from this research.
What this research studies
This research focuses on creating pre-clinical models that simulate infectious diseases to better understand their mechanisms and potential treatments. By using these models, researchers aim to evaluate the effectiveness of medical countermeasures and develop new strategies for combating infections. Patients may benefit from advancements in treatment options that arise from the insights gained through these models.
Why it matters
Potential benefit: If successful, this research could lead to improved treatments and preventive measures for infectious diseases.
How similar studies have gone: Other research has shown success in using pre-clinical models to develop effective treatments for infectious diseases, indicating a promising approach.
Where this research is happening
-
Pennsylvania State Univ Hershey Med Ctr
Hershey, United States Active
Related research
Other NIH-funded projects on the same topics.
-
Cognitive behavioral therapy and trazodone for insomnia phenotypes with high blood pressure
A clinical study tests how CBT-I and the sleep drug trazodone work for adults with insomnia and high blood pressure, focusing on a specific sleep duration pattern.
-
Understanding the STIM/Orai Calcium Signaling Pathway in Cancer
Researchers are studying how STIM and Orai proteins control calcium signals inside cells and how this affects cancer-related growth and remodeling, with hopes to find ways to influence these signals for better treatments.
-
Understanding how some Amish communities maintain high birth rates in modern times
A project will build a large, time-sensitive dataset to understand why Amish families keep having many children, even as broader society has much lower birth rates.
-
Scoliosis and neurosurgical factors in myelomeningocele: a clinic registry study
This project uses registry data from Penn State’s Spina Bifida Clinic to understand how brain and spine-related issues influence when and why scoliosis surgery is needed in people with myelomeningocele.
-
Understanding how damaged stomach cells revert to a repair state to prevent cancer
Researchers are studying how certain stomach cells re-enter the cell cycle to aid tissue repair, and how this process might lead to metaplasia or cancer if it goes wrong.
-
Aging, cell aging, and how MCPyV causes Merkel cell carcinoma
Aging and aging-related changes in skin cells may help a common virus (MCPyV) persist and potentially lead to a rare skin cancer in people with weaker immune systems.
About this research
- This is an active NIH-funded research project — typically early-stage science, not a clinical trial accepting patient enrollment.
- Some NIH-funded labs run parallel clinical studies or seek volunteers for related work. To check, contact the principal investigator or institution listed above.
- For full project details, budget, and progress reports, visit the official NIH RePORTER page.