Developing less invasive methods to record and modulate brain activity

Minimally Invasive Endovascular Neural Interfaces for Brain Recording and Modulation

NIH-funded research Stanford University · NIH-11075238

This study is exploring a new way to safely connect to the brain using tiny, flexible devices that can be delivered through blood vessels, which could help improve treatments for brain conditions without the need for risky surgery.

Quick facts

Grant typeCareer grant
Study typeNIH-funded research
Funding institutionStanford University NIH-funded
Lab location1 site (Stanford, United States)
Project IDNIH-11075238 on NIH RePORTER

What this research studies

This research focuses on creating a new type of neuroelectronic interface that can be delivered through blood vessels to record and modulate brain activity without the need for invasive open-skull surgery. By using flexible probes that can navigate into small cortical vessels, the project aims to minimize risks such as bleeding and infection associated with traditional methods. The research will involve testing these probes in animal models to ensure they can effectively monitor and stimulate brain activity over the long term. Ultimately, this technology could lead to safer treatments for various neurological diseases.

Who could benefit from this research

Good fit: Ideal candidates for this research would include individuals suffering from drug-resistant neurological conditions, such as advanced Alzheimer's disease or other chronic neurological disorders.

Not a fit: Patients with non-neurological conditions or those who do not have drug-resistant neurological diseases may not benefit from this research.

Why it matters

Potential benefit: If successful, this research could provide safer and more effective treatment options for patients with drug-resistant neurological diseases.

How similar studies have performed: Previous research has shown promise in using endovascular techniques for brain recording, indicating that this approach could be a viable alternative to traditional methods.

Where this research is happening

Stanford, United States

Researchers

About this research

  1. This is an active NIH-funded research project — typically early-stage science, not a clinical trial accepting patient enrollment.
  2. Some NIH-funded labs run parallel clinical studies or seek volunteers for related work. To check, contact the principal investigator or institution listed above.
  3. For full project details, budget, and progress reports, visit the official NIH RePORTER page below.
Conditions Acquired brain injuryAlzheimer disease dementiaAlzheimer syndromeAlzheimer's Disease
Last reviewed 2026-06-09 by the Find a Trial editorial team. Information on this page is for educational purposes and is not medical advice. Always consult qualified healthcare professionals about clinical trial participation.