Developing gene editing tools for geckos
Official title: Collaborative Research: EDGE FGT: DEVELOPMENT OF FUNCTIONAL GENETIC TOOLS IN GECKOS
Funded at Marquette University · NIH-11009982 · Data updated 2026-11-12
This study is working on new ways to use gene editing in geckos to help scientists learn more about how genes work in lizards, and it will also provide training for other researchers to use these techniques.
Quick facts
| Grant type | R01 grant |
|---|---|
| Study type | NIH-funded research |
| Funding institution | Marquette University NIH-funded |
| Lab location | 1 site (Milwaukee, United States) |
| Project start | March 1, 2023 |
| Project end | December 31, 2025 |
| Funding year | 2025 |
| Award (this year) | $326,213 |
| NIH project number | 5R01HG013006-03 |
| Project ID | NIH-11009982 on NIH RePORTER |
Who could benefit from this research
✓Could help
Ideal candidates for participation or benefit from this research would be researchers and scientists interested in functional genomics and gene editing technologies.
✕Less likely to help
Patients who are not involved in genetic research or do not have a specific interest in gene editing methodologies may not receive direct benefits from this research.
What this research studies
This research focuses on creating advanced gene editing techniques using CRISPR/Cas technology specifically for geckos, a diverse group of lizards. By establishing these methods, the project aims to enhance our understanding of gene functions across various lizard species, which currently have limited gene editing capabilities. The research will also include the development of training materials and workshops to share these new techniques with other researchers. Ultimately, this work seeks to broaden the functional genomic toolkit available for studying the biology of squamates.
Why it matters
Potential benefit: If successful, this research could significantly enhance the ability to study gene functions in a wider variety of lizard species, leading to breakthroughs in our understanding of genetics and evolution.
How similar studies have gone: Other research has successfully developed gene editing tools in various species, but this specific approach for geckos is relatively novel and untested.
Where this research is happening
-
Marquette University
Milwaukee, United States Active
Researchers
- Principal investigator: Gamble, Anthony B — Marquette University
- Study coordinator: Gamble, Anthony B
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About this research
- This is an active NIH-funded research project — typically early-stage science, not a clinical trial accepting patient enrollment.
- Some NIH-funded labs run parallel clinical studies or seek volunteers for related work. To check, contact the principal investigator or institution listed above.
- For full project details, budget, and progress reports, visit the official NIH RePORTER page.