Developing advanced x-ray detectors for studying biological systems
Official title: High Speed Large Area Detector for LCLS
Funded at Stanford University · NIH-10632500 · Data updated 2026-11-12
This study is working on improving x-ray technology to help scientists take clearer pictures of tiny biological structures, like proteins, without damaging them, so they can better understand how these important parts of our bodies work.
Quick facts
| Grant type | NIH-funded research |
|---|---|
| Study type | NIH-funded research |
| Funding institution | Stanford University NIH-funded |
| Lab location | 1 site (Stanford, United States) |
| Project start | April 15, 2023 |
| Project end | October 14, 2025 |
| Funding year | 2023 |
| Award (this year) | $1,965,000 |
| NIH project number | 1S10OD034436-01 |
| Project ID | NIH-10632500 on NIH RePORTER |
Who could benefit from this research
✓Could help
Ideal candidates for participation or benefit from this research include individuals with conditions that require detailed molecular understanding, such as cancer or genetic disorders.
✕Less likely to help
Patients with conditions that do not involve molecular or structural biological studies may not receive direct benefits from this research.
What this research studies
This research focuses on creating next-generation x-ray detector technology to enhance the capabilities of X-ray Free Electron Lasers (FEL) in structural biology. By utilizing extremely short pulses of x-rays, the project aims to capture detailed information about the structure and dynamics of biological systems before radiation damage occurs. This approach allows for high-resolution data collection under physiologically relevant conditions, enabling the study of fast biological processes. The modernization of outdated detector systems at the Linac Coherent Light Source (LCLS) is a key component of this initiative.
Why it matters
Potential benefit: If successful, this research could significantly improve our understanding of biological processes at the molecular level, leading to advancements in drug development and disease treatment.
How similar studies have gone: Previous research in femtosecond crystallography has shown promising results, indicating that this approach has the potential for significant advancements in structural biology.
Where this research is happening
-
Stanford University
Stanford, United States Active
Researchers
- Principal investigator: Batyuk, Alex — Stanford University
- Study coordinator: Batyuk, Alex
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About this research
- This is an active NIH-funded research project — typically early-stage science, not a clinical trial accepting patient enrollment.
- Some NIH-funded labs run parallel clinical studies or seek volunteers for related work. To check, contact the principal investigator or institution listed above.
- For full project details, budget, and progress reports, visit the official NIH RePORTER page.