Developing advanced tools to analyze molecular events in living systems
Official title: Bioorthogonal temporospatial tools
Funded at Massachusetts General Hospital · NIH-11059151 · Data updated 2026-11-12
This study is working on new tools that help scientists see and understand tiny changes in living organisms more clearly, which could lead to better treatments for different health conditions.
Quick facts
| Grant type | NIH-funded research |
|---|---|
| Study type | NIH-funded research |
| Funding institution | Massachusetts General Hospital NIH-funded |
| Lab location | 1 site (Boston, United States) |
| Project start | July 1, 2023 |
| Project end | April 30, 2028 |
| Funding year | 2025 |
| Award (this year) | $417,500 |
| NIH project number | 5R35GM150508-03 |
| Project ID | NIH-11059151 on NIH RePORTER |
Who could benefit from this research
✓Could help
Ideal candidates for participation or benefit from this research include individuals with conditions that involve complex molecular signaling or cellular interactions.
✕Less likely to help
Patients with conditions that do not involve molecular or cellular analysis may not receive direct benefits from this research.
What this research studies
This research focuses on creating innovative chemical tools that allow scientists to analyze and visualize molecular events in living organisms with high precision regarding time and location. By employing advanced bioorthogonal chemistries, the project aims to enhance the detection of rare biological events and improve the accuracy of tracking cellular histories. Patients may benefit from these advancements as they could lead to better understanding and treatment of various biological conditions through improved molecular imaging techniques. The research will utilize multi-layered molecular architectures to achieve these goals.
Why it matters
Potential benefit: If successful, this research could significantly enhance the ability to visualize and understand complex biological processes, leading to improved diagnostic and therapeutic strategies for patients.
How similar studies have gone: Previous research has shown promise in using bioorthogonal chemistry for molecular imaging, indicating that this approach has potential for success.
Where this research is happening
-
Massachusetts General Hospital
Boston, United States Active
Researchers
- Principal investigator: Carlson, Jonathan — Massachusetts General Hospital
- Study coordinator: Carlson, Jonathan
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About this research
- This is an active NIH-funded research project — typically early-stage science, not a clinical trial accepting patient enrollment.
- Some NIH-funded labs run parallel clinical studies or seek volunteers for related work. To check, contact the principal investigator or institution listed above.
- For full project details, budget, and progress reports, visit the official NIH RePORTER page.