Developing advanced technology to study protein complexes
Official title: Native Mass Spectrometry Guided Structural Biology Center
Funded at Ohio State University · NIH-10931333 · Data updated 2026-11-12
This study is exploring new technology to better understand how protein complexes work, which could help improve treatments for diseases like AIDS, so patients can benefit from more effective options in the future.
Quick facts
| Grant type | NIH-funded research |
|---|---|
| Study type | NIH-funded research |
| Funding institution | Ohio State University NIH-funded |
| Lab location | 1 site (Columbus, UNITED STATES) |
| Project start | September 19, 2023 |
| Project end | July 31, 2028 |
| Funding year | 2024 |
| Award (this year) | $1,293,476 |
| NIH project number | 5RM1GM149374-02 |
| Project ID | NIH-10931333 on NIH RePORTER |
Who could benefit from this research
✓Could help
Ideal candidates for participation or benefit from this research include individuals affected by diseases linked to protein complexes, such as those living with HIV/AIDS.
✕Less likely to help
Patients with conditions unrelated to protein complex dysfunction may not receive direct benefits from this research.
What this research studies
This research focuses on creating innovative technology for analyzing the structure and behavior of protein complexes, which are crucial for understanding various diseases, including AIDS. By utilizing native mass spectrometry, the project aims to provide detailed insights into the composition, stability, and interactions of these proteins under different conditions. Patients may benefit from the advancements in treatment options that arise from a better understanding of how these proteins function and interact in the body.
Why it matters
Potential benefit: If successful, this research could lead to improved therapies for diseases related to protein dysfunction, including AIDS.
How similar studies have gone: Previous research utilizing mass spectrometry for structural biology has shown promising results, indicating that this approach is both viable and potentially transformative.
Where this research is happening
-
Ohio State University
Columbus, United States Active
Researchers
- Principal investigator: Wysocki, Vicki H. — Ohio State University
- Study coordinator: Wysocki, Vicki H.
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About this research
- This is an active NIH-funded research project — typically early-stage science, not a clinical trial accepting patient enrollment.
- Some NIH-funded labs run parallel clinical studies or seek volunteers for related work. To check, contact the principal investigator or institution listed above.
- For full project details, budget, and progress reports, visit the official NIH RePORTER page.