Developing advanced laser particles for faster analysis of biological samples
Official title: Multi-color laser particles for high-throughput pooled analysis
Funded at Massachusetts General Hospital · NIH-11128328 · Data updated 2026-11-12
This study is working on a new way to use colorful laser tags to help scientists quickly and accurately analyze biological samples, which could lead to exciting discoveries in medicine and drug development.
Quick facts
| Grant type | R01 grant |
|---|---|
| Study type | NIH-funded research |
| Funding institution | Massachusetts General Hospital NIH-funded |
| Lab location | 1 site (Boston, United States) |
| Project start | June 1, 2023 |
| Project end | May 31, 2027 |
| Funding year | 2025 |
| Award (this year) | $478,694 |
| NIH project number | 5R01EB034687-03 |
| Project ID | NIH-11128328 on NIH RePORTER |
Who could benefit from this research
✓Could help
Ideal candidates for this research are individuals undergoing diagnostic testing or treatment for conditions that require high-throughput biological analysis.
✕Less likely to help
Patients who do not require high-throughput analysis or those with conditions that are not addressed by the technologies being developed may not benefit from this research.
What this research studies
This research focuses on creating innovative optical barcoding technology using multi-color laser particles to enhance the analysis of biological samples. By tagging cells or microbeads with these unique identifiers, the project aims to significantly improve the speed and accuracy of high-throughput assays, such as flow cytometry and immunoassays. The methodology involves developing a range of semiconductor laser particles that can be used to analyze multiple parameters simultaneously, which could lead to breakthroughs in biological discovery and drug development.
Why it matters
Potential benefit: If successful, this research could lead to faster and more cost-effective methods for analyzing biological samples, ultimately improving patient diagnostics and treatment options.
How similar studies have gone: Previous research has shown success with optical barcoding technologies, indicating a promising potential for this novel approach.
Where this research is happening
-
Massachusetts General Hospital
Boston, United States Active
Researchers
- Principal investigator: Yun, Seok-Hyun Andy — Massachusetts General Hospital
- Study coordinator: Yun, Seok-Hyun Andy
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About this research
- This is an active NIH-funded research project — typically early-stage science, not a clinical trial accepting patient enrollment.
- Some NIH-funded labs run parallel clinical studies or seek volunteers for related work. To check, contact the principal investigator or institution listed above.
- For full project details, budget, and progress reports, visit the official NIH RePORTER page.